SynthesisPsychological medicine2016
Self-injurious thoughts and behaviors as risk factors for future suicide ideation, attempts, and death: a meta-analysis of longitudinal studies.
Synthesis in Psychological medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 569 papers, 10 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
569 citing papers in PubMed, 10 syntheses or guidelines pooled it, 1,268 citations in OpenAlex.
- The Relationship Between Anger and Nonsuicidal Self-Injury: A Meta-Analysis.Suicide & life-threatening behavior · 2026Pooled it
- Therapeutic interventions for adolescent suicidal behavior and self-harm: an umbrella review for developing clinical practice guidelines in South Korea.BMC psychiatry · 2026Pooled it
- Effects of interventions for self-harm in children and adolescents: a systematic review and meta-analysis.European child & adolescent psychiatry · 2026Pooled it
- Can machine learning predict non-suicidal self-injury? A systematic review and meta-analysis.Frontiers in public health · 2026Pooled it
- Machine learning algorithms and their predictive accuracy for suicide and self-harm: Systematic review and meta-analysis.PLoS medicine · 2025Pooled it
- The Lifetime Prevalence of Non-Suicidal Self-Injury in Children and Adolescents With Eating Disorders-A Systematic Review and Meta-Analysis.European eating disorders review : the journal of the Eating Disorders Association · 2025Pooled it
- Suicidal ideation, attempted suicide and determinants among prisoners in Ethiopia 2024: a systematic review and meta-analysis.BMC psychiatry · 2025Pooled it
- Pooled it
- Impulsivity and non-suicidal self-injury in adolescents: a systematic review and meta-analysis of longitudinal studies.Frontiers in psychiatry · 2025Pooled it
- Prevention of self-harm and suicide in young people up to the age of 25 in education settings.The Cochrane database of systematic reviews · 2024Pooled it
- Hospital-Based Psychosocial Case Management and Suicide Prevention in South Korea: A Randomized Clinical Trial.JAMA network open · 2026Trial
- Effectiveness of 13-week dialectical behavior therapy skills training for non-suicidal self-injury: a multi-center randomized clinical trial in China.Psychological medicine · 2026Trial
- Trial
- Suicidal ideation trajectories among adults following psychiatric hospitalization.Behaviour research and therapy · 2026Trial
- Effects of a Whole-School Prevention Program Targeting Mental Health and Nonsuicidal Self-Injury in Swedish Adolescents: A Cluster-Randomized Experimental Study with Longitudinal Follow-Up.Journal of youth and adolescence · 2026Trial
- Cost-Effectiveness of Internet-Delivered Emotion Regulation Therapy for Adolescents With Nonsuicidal Self-Injury: Within-Trial Analysis of a Randomized Controlled Trial.JMIR mental health · 2025Trial
- Efficacy of a brief psychological intervention for adolescents with recent suicide attempt: A randomized clinical trial.European psychiatry : the journal of the Association of European Psychiatrists · 2025Trial
- The Prevalence and Incidence of Suicidal Thoughts and Behavior in a Smartphone-Delivered Treatment Trial for Body Dysmorphic Disorder: Cohort Study.JMIR mental health · 2025Trial
- Preventing suicide with Safe Alternatives for Teens and Youths (SAFETY): a randomised feasibility trial.BMJ mental health · 2025Trial
- Comparison between clinician and machine learning prediction in a randomized controlled trial for nonsuicidal self-injury.BMC psychiatry · 2024Trial
509 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundA history of self-injurious thoughts and behaviors (SITBs) is consistently cited as one of the strongest predictors of future suicidal behavior. However, stark discrepancies in the literature raise questions about the true magnitude of these associations. The objective of this study is to examine the magnitude and clinical utility of the associations between SITBs and subsequent suicide ideation, attempts, and death.
methodWe searched PubMed, PsycInfo, and Google Scholar for papers published through December 2014. Inclusion required that studies include at least one longitudinal analysis predicting suicide ideation, attempts, or death using any SITB variable. We identified 2179 longitudinal studies; 172 met inclusion criteria.
resultsThe most common outcome was suicide attempt (47.80%), followed by death (40.50%) and ideation (11.60%). Median follow-up was 52 months (mean = 82.52, s.d. = 102.29). Overall prediction was weak, with weighted mean odds ratios (ORs) of 2.07 [95% confidence interval (CI) 1.76-2.43] for ideation, 2.14 (95% CI 2.00-2.30) for attempts, and 1.54 (95% CI 1.39-1.71) for death. Adjusting for publication bias further reduced estimates. Diagnostic accuracy analyses indicated acceptable specificity (86-87%) and poor sensitivity (10-26%), with areas under the curve marginally above chance (0.60-0.62). Most risk factors generated OR estimates of <2.0 and no risk factor exceeded 4.5. Effects were consistent regardless of sample severity, sample age groups, or follow-up length.
conclusionsPrior SITBs confer risk for later suicidal thoughts and behaviors. However, they only provide a marginal improvement in diagnostic accuracy above chance. Addressing gaps in study design, assessment, and underlying mechanisms may prove useful in improving prediction and prevention of suicidal thoughts and behaviors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.