Evidence map›Paper›PMID 26370696›Full record

ReviewCurrent diabetes reports2015

Sex-specific differential in risk of diabetes-related macrovascular outcomes.

Amanda Lyon, Elizabeth A Jackson, Rita R Kalyani, Dhananjay Vaidya, Catherine Kim

Abstract readReview
In one paragraph

Review in Current diabetes reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Position Statement on Cardiometabolic Health Across the Woman's Life Course - 2025.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2025
    Article
  5. Molecular Mechanisms of Adenosine Stress T1 Mapping.Circulation. Cardiovascular imaging · 2021
    Article
  6. Article
  7. Obesity and cardiovascular disease in women.International journal of obesity (2005) · 2020
    Review
  8. Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Amanda LyonDepartment of Medicine, University of Michigan, 1500 E Medical Center Drive, Ann Arbor, MI, 48109, USA. amly@med.umich.edu.
Elizabeth A JacksonDepartment of Medicine, Division of Cardiovascular Medicine, University of Michigan, 24 Frank Lloyd Wright Drive, Ann Arbor, MI, 48106, USA. lisjacks@med.umich.edu.
Rita R KalyaniDepartment of Medicine, Johns Hopkins University, 1830 E Monument St # 333, Baltimore, MD, 21287, USA. rrastogi@jhmi.edu.
Dhananjay VaidyaDepartment of Medicine, Johns Hopkins University, 1830 E Monument St # 333, Baltimore, MD, 21287, USA. dvaidya1@jhmi.edu.
Catherine KimDepartments of Medicine, Obstetrics & Gynecology, and Epidemiology, University of Michigan, 2800 Plymouth Road, Building 16, Room 430W, Ann Arbor, MI, 48109, USA. cathkim@umich.edu.

Funding

Research BaseP30DK092926 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MARY ELLEN MICHELE HEISLER, ADESUWA B OLOMU · 2011 to 2026
$10.0M
JHU-UMD Diabetes Research CenterP30DK079637 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI AHIMA, REXFORD S. · 2013 to 2017
$9.7M
NIDDK NIH HHS P30 DK079637NIDDK NIH HHS P30 DK092926
6 · The paper itself

Abstract

Reports from recent studies suggest that diabetes confers a higher risk of cardiovascular disease in women compared to men. Larger studies, including meta-analyses, report that women with diabetes have a 44 % greater risk of incident coronary heart disease and a 27 % greater risk of incident stroke compared to men with diabetes. In this article, we summarize results from longitudinal studies that examine sex differences in risk factors for and rates of macrovascular complications from diabetes. We also discuss possible mechanisms for increased cardiovascular risk associated with diabetes in women compared to men, including the clustering of hypertension, obesity, and elevated triglycerides, the possible contribution of hormonal differences, and sex differences in the prescription of and adherence to pharmacologic treatment. In conclusion, diabetes is associated with a slightly higher risk of cardiovascular disease in women compared to men. Future studies should further explore the reasons underlying imperfect use of medications that lower cardiovascular risk in both women and men with diabetes.

Indexed as

Diabetes ComplicationsDiabetes MellitusCardiovascular DiseasesFemaleHumansMaleRisk FactorsSex CharacteristicsStrokeCardiovascularCoronary heart diseaseDiabetesSexStroke

Identifiers

PMID26370696
PMCPMC5511034

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.