ArticleScientific reports2015
Complete mitochondrial genome of the medicinal fungus Ophiocordyceps sinensis.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed.
- Article
- Comparative Mitogenomics Reveals Intron Dynamics and Mitochondrial Gene Expression Shifts in Domesticated and WildJournal of fungi (Basel, Switzerland) · 2026Article
- Utilizing mitochondrial genome sequences to understand population diversity amongFrontiers in fungal biology · 2026Article
- Characterization and Phylogenetic Analysis of the Complete Mitogenomes ofJournal of fungi (Basel, Switzerland) · 2025Article
- Complete mitochondrial genome ofMitochondrial DNA. Part B, Resources · 2025Article
- Comparative Analysis of the Mitochondrial Genome Sequences ofJournal of fungi (Basel, Switzerland) · 2024Article
- Comparative Mitogenomics Analysis Revealed Evolutionary Divergence amongInternational journal of molecular sciences · 2024Article
- Article
- Mitochondrial genome of Cordyceps blackwelliae: organization, transcription, and evolutionary insights into Cordyceps.IMA fungus · 2023Article
- Article
- Systematic analyses with genomic and metabolomic insights reveal a new species,Frontiers in microbiology · 2023Article
- Comparative analysis of the complete mitochondrial genomes of four cordyceps fungi.Ecology and evolution · 2022Article
- Characterization and phylogenetic analysis of the complete mitochondrial genome of the pathogenic fungus Ilyonectria destructans.Scientific reports · 2022Article
- The complete mitochondrial genome of Ophiocordyceps gracilis and its comparison with related species.IMA fungus · 2021Article
- The Ubiquity and Development-Related Abundance Dynamics ofMicroorganisms · 2021Article
- Chinese caterpillar fungus (Ophiocordyceps sinensis) in China: Current distribution, trading, and futures under climate change and overexploitation.The Science of the total environment · 2021Article
- Revealing the high variability on nonconserved core and mobile elements of Austropuccinia psidii and other rust mitochondrial genomes.PloS one · 2021Article
- A Comparative Analyses of the Complete Mitochondrial Genomes of Fungal Endosymbionts inInternational journal of genomics · 2021Article
- Comparative Mitogenomic Analysis and the Evolution ofFrontiers in microbiology · 2021Article
- Intra-specific comparison of mitochondrial genomes reveals host gene fragment exchange via intron mobility in Tremella fuciformis.BMC genomics · 2020Article
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As part of a genome sequencing project for Ophiocordyceps sinensis, strain 1229, a complete mitochondrial (mt) genome was assembled as a single circular dsDNA of 157,510 bp, one of the largest reported for fungi. Conserved genes including the large and small rRNA subunits, 27 tRNA and 15 protein-coding genes, were identified. In addition, 58 non-conserved open reading frames (ncORFs) in the intergenic and intronic regions were also identified. Transcription analyses using RNA-Seq validated the expression of most conserved genes and ncORFs. Fifty-two introns (groups I and II) were found within conserved genes, accounting for 68.5% of the genome. Thirty-two homing endonucleases (HEs) with motif patterns LAGLIDADG (21) and GIY-YIG (11) were identified in group I introns. The ncORFs found in group II introns mostly encoded reverse transcriptases (RTs). As in other hypocrealean fungi, gene contents and order were found to be conserved in the mt genome of O. sinensis, but the genome size was enlarged by longer intergenic regions and numerous introns. Intergenic and intronic regions were composed of abundant repetitive sequences usually associated with mobile elements. It is likely that intronic ncORFs, which encode RTs and HEs, may have contributed to the enlarged mt genome of O. sinensis.
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