ReviewCurrent opinion in genetics & development2015
Genomic investigations of evolutionary dynamics and epistasis in microbial evolution experiments.
Review in Current opinion in genetics & development, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
35 citing papers in PubMed.
- Adaptive laboratory evolution of Micrococcus luteus and identification of genes associated with radioresistance through genome-wide association study.Scientific reports · 2025Article
- Patterns of Fitness and Gene Expression Epistasis Generated by Beneficial Mutations in the rho and rpoB Genes of Escherichia coli during High-Temperature Adaptation.Molecular biology and evolution · 2024Article
- Article
- Long-range linkage effects in adapting sexual populations.Scientific reports · 2023Article
- An Amino Acid Substitution in Elongation Factor EF-G1A Alters the Antibiotic Susceptibility of Pseudomonas aeruginosa LasR-Null Mutants.Journal of bacteriology · 2023Article
- Embracing Complexity: Yeast Evolution Experiments Featuring Standing Genetic Variation.Journal of molecular evolution · 2023Review
- Article
- Article
- A mutational hotspot that determines highly repeatable evolution can be built and broken by silent genetic changes.Nature communications · 2021Article
- Forecasting of phenotypic and genetic outcomes of experimental evolution in Pseudomonas protegens.PLoS genetics · 2021Article
- Intra-Population Competition during Adaptation to Increased Temperature in an RNA Bacteriophage.International journal of molecular sciences · 2021Article
- A trimethoprim derivative impedes antibiotic resistance evolution.Nature communications · 2021Article
- Experimental Evolution in Plant-Microbe Systems: A Tool for Deciphering the Functioning and Evolution of Plant-Associated Microbial Communities.Frontiers in microbiology · 2021Review
- Review
- Adaptive response to iterative passages of five Lactobacillus species in simulated vaginal fluid.BMC microbiology · 2020Article
- Rampant loss of social traits during domestication of a Bacillus subtilis natural isolate.Scientific reports · 2020Article
- An Evolutionary Model of Progression to AIDS.Microorganisms · 2020Article
- Lactobacillus rhamnosus GG Genomic and Phenotypic Stability in an Industrial Production Process.Applied and environmental microbiology · 2020Article
- Article
- Emerging Priorities for Microbiome Research.Frontiers in microbiology · 2020Review
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Microbial evolution experiments enable us to watch adaptation in real time, and to quantify the repeatability and predictability of evolution by comparing identical replicate populations. Further, we can resurrect ancestral types to examine changes over evolutionary time. Until recently, experimental evolution has been limited to measuring phenotypic changes, or to tracking a few genetic markers over time. However, recent advances in sequencing technology now make it possible to extensively sequence clones or whole-population samples from microbial evolution experiments. Here, we review recent work exploiting these techniques to understand the genomic basis of evolutionary change in experimental systems. We first focus on studies that analyze the dynamics of genome evolution in microbial systems. We then survey work that uses observations of sequence evolution to infer aspects of the underlying fitness landscape, concentrating on the epistatic interactions between mutations and the constraints these interactions impose on adaptation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.