Evidence map›Paper›PMID 26370423›Full record

ReviewClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2016

Non-coding RNAs deregulation in oral squamous cell carcinoma: advances and challenges.

T Yu, C Li, Z Wang, K Liu, C Xu, Q Yang, Y Tang, Y Wu

Abstract readReview
PubMed Publisher
In one paragraph

Review in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

T YuDepartment of Head and Neck Oncology Surgery, Sichuan Cancer Hospital, No. 55, Sec. 4, Renminnan Road, 610041, Chengdu, Sichuan, People's Republic of China. cjyt2006@163.com.
C LiDepartment of Head and Neck Oncology Surgery, Sichuan Cancer Hospital, No. 55, Sec. 4, Renminnan Road, 610041, Chengdu, Sichuan, People's Republic of China.
Z WangDepartment of Head and Neck Oncology Surgery, Sichuan Cancer Hospital, No. 55, Sec. 4, Renminnan Road, 610041, Chengdu, Sichuan, People's Republic of China.
K LiuDepartment of Head and Neck Oncology Surgery, Sichuan Cancer Hospital, No. 55, Sec. 4, Renminnan Road, 610041, Chengdu, Sichuan, People's Republic of China.
C XuDepartment of Head and Neck Oncology Surgery, Sichuan Cancer Hospital, No. 55, Sec. 4, Renminnan Road, 610041, Chengdu, Sichuan, People's Republic of China.
Q YangDepartment of Head and Neck Oncology Surgery, Sichuan Cancer Hospital, No. 55, Sec. 4, Renminnan Road, 610041, Chengdu, Sichuan, People's Republic of China.
Y TangDepartment of Head and Neck Oncology Surgery, Sichuan Cancer Hospital, No. 55, Sec. 4, Renminnan Road, 610041, Chengdu, Sichuan, People's Republic of China.
Y WuState Key Laboratory of Oral Diseases, West China School of Stomatology, Sichuan University, No. 14, Sec. 3, Renminnan Road, 610041, Chengdu, Sichuan, People's Republic of China. vince8181@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral squamous cell carcinoma (OSCC) is a common cause of cancer death. Despite decades of improvements in exploring new treatments and considerable advance in multimodality treatment, satisfactory curative rates have not yet been reached. The difficulty of early diagnosis and the high prevalence of metastasis associated with OSCC contribute to its dismal prognosis. In the last few decades the emerging data from both tumor biology and clinical trials led to growing interest in the research for predictive biomarkers. Non-coding RNAs (ncRNAs) are promising biomarkers. Among numerous kinds of ncRNAs, short ncRNAs, such as microRNAs (miRNAs), have been extensively investigated with regard to their biogenesis, function, and importance in carcinogenesis. In contrast to miRNAs, long non-coding RNAs (lncRNAs) are much less known concerning their functions in human cancers especially in OSCC. The present review highlighted the roles of miRNAs and newly discovered lncRNAs in oral tumorigenesis, metastasis, and their clinical implication.

Indexed as

Biomarkers, TumorCarcinoma, Squamous CellHumansMouth NeoplasmsPrognosisRNA, UntranslatedBiomarkers, TumorRNA, UntranslatedLong non-coding RNAsmicroRNAsNon-coding RNAsOral squamous cell carcinoma

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.