ArticleReproduction (Cambridge, England)2015
Mating induces the expression of immune- and pH-regulatory genes in the utero-vaginal junction containing mucosal sperm-storage tubuli of hens.
Article in Reproduction (Cambridge, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 43 citations in OpenAlex.
- Dynamic metabolomics of uterine fluid of laying hens: Key metabolites and pathways governing sperm motility and functional longevity.Poultry science · 2026Article
- Unique Physiological Mechanisms of Sperm Storage and Prolonged Sperm Survival in Hen Oviducts: A Review.The journal of poultry science · 2025Review
- Transcriptomic insights into early responses of the uterovaginal junction and vagina to avian influenza virus infection in turkey breeder hens.Frontiers in physiology · 2025Article
- Identification of genes associated with sperm storage capacity in hens at different times after insemination by RNA-seq and Ribo-seq.BMC genomics · 2024Article
- Transcriptome identification of genes associated with uterus-vagina junction epithelial folds formation in chicken hens.Poultry science · 2023Article
- Turkey hen sperm storage tubule transcriptome response to artificial insemination and the presence of semen.Frontiers in physiology · 2023Article
- Prolonged repeated inseminations trigger a local immune response and accelerate aging of the uterovaginal junction in turkey hens.Frontiers in physiology · 2023Article
- Seminal Plasma: Relevant for Fertility?International journal of molecular sciences · 2021Review
- Transcriptome analysis and identification of age-associated fertility decreased genes in hen uterovaginal junction.Poultry science · 2021Article
- In vivo measurement of pH and COScientific reports · 2021Article
- Does the Act of Copulation per se, without Considering Seminal Deposition, Change the Expression of Genes in the Porcine Female Genital Tract?International journal of molecular sciences · 2020Article
- Natural Mating Differentially Triggers Expression of Glucocorticoid Receptor (NR3C1)-Related Genes in the Preovulatory Porcine Female Reproductive Tract.International journal of molecular sciences · 2020Article
- Transcriptome analysis and identification of genes associated with chicken sperm storage duration.Poultry science · 2020Article
- Investigation of the impact of gut microbiotas on fertility of stored sperm by types of hens.Poultry science · 2020Article
- Role of genome-wide mRNA-seq profiling in understanding the long-term sperm maintenance in the storage tubules of laying hens.Tropical animal health and production · 2019Article
- Expression of Immune Regulatory Genes in the Porcine Internal Genital Tract Is Differentially Triggered by Spermatozoa and Seminal Plasma.International journal of molecular sciences · 2019Article
- Finite cell lines of turkey sperm storage tubule cells: ultrastructure and protein analysis.Poultry science · 2018Article
- Transcriptome sequencing reveals key potential long non-coding RNAs related to duration of fertility trait in the uterovaginal junction of egg-laying hens.Scientific reports · 2018Article
- Conserved gene expression in sperm reservoirs between birds and mammals in response to mating.BMC genomics · 2017Article
- Global analysis of differential gene expression related to long-term sperm storage in oviduct of Chinese Soft-Shelled Turtle Pelodiscus sinensis.Scientific reports · 2016Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The female chicken, as with other species with internal fertilization, can tolerate the presence of spermatozoa within specialized sperm-storage tubuli (SST) located in the mucosa of the utero-vaginal junction (UVJ) for days or weeks, without eliciting an immune response. To determine if the oviduct alters its gene expression in response to sperm entry, segments from the oviduct (UVJ, uterus, isthmus, magnum and infundibulum) of mated and unmated (control) hens, derived from an advanced inter-cross line between Red Junglefowl and White Leghorn, were explored 24 h after mating using cDNA microarray analysis. Mating shifted the expression of fifteen genes in the UVJ (53.33% immune-modulatory and 20.00% pH-regulatory) and seven genes in the uterus, none of the genes in the latter segment overlapping the former (with the differentially expressed genes themselves being less related to immune-modulatory function). The other oviductal segments did not show any significant changes. These findings suggest sperm deposition causes a shift in expression in the UVJ (containing mucosal SST) and the uterus for genes involved in immune-modulatory and pH-regulatory functions, both relevant for sperm survival in the hen's oviduct.
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