Evidence map›Paper›PMID 26369925›Full record

ReviewPediatric nephrology (Berlin, Germany)2016

Growth hormone therapy in children with CKD after more than two decades of practice.

Lesley Rees

Abstract readReview
PubMed Publisher
In one paragraph

Review in Pediatric nephrology (Berlin, Germany), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

  1. Guideline
  2. Linear growth in pediatric kidney transplant recipients.Pediatric nephrology (Berlin, Germany) · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Renal effects of growth hormone in health and in kidney disease.Pediatric nephrology (Berlin, Germany) · 2021
    Article
  8. Article
  9. Article
  10. Treatment of Growth Retardation in a Child with CKD.Clinical journal of the American Society of Nephrology : CJASN · 2019
    Article
  11. Article
  12. Review
  13. Pubertal development in children with chronic kidney disease.Pediatric nephrology (Berlin, Germany) · 2017
    Review
  14. Article
  15. Article
  16. Chronic kidney disease in children.Clinical kidney journal · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Lesley ReesGt Ormond St Hospital for Children NHS Foundation Trust, London, WC1N3JH, UK. lesley.rees@gosh.nhs.uk.
Great Ormond Street Hospital for Children NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review focuses on the evidence for the efficacy and safety of recombinant human growth hormone (rhGH) therapy in children with all stages of chronic kidney disease (CKD) and at all ages. It describes the improving height prognosis for our patients both with and without rhGH; explains the underlying hormonal abnormalities that provide the rationale for rhGH use in CKD and the endocrine changes that accompany treatment; and views on who warrants treatment, with what dose, and how long for.

Indexed as

Body HeightChildGrowth DisordersGrowth HormoneHuman Growth HormoneHumansRecombinant ProteinsRenal Insufficiency, ChronicGrowth HormoneHuman Growth HormoneRecombinant ProteinsFinal heightGrowthGrowth hormone

Identifiers

PMID26369925
OpenAlexW1961301438

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.