Evidence map›Paper›PMID 26369829›Full record

ArticleLeukemia2015

Effectiveness of azacitidine for the treatment of higher-risk myelodysplastic syndromes in daily practice: results from the Dutch population-based PHAROS MDS registry.

A G Dinmohamed, Y van Norden, O Visser, E F M Posthuma, P C Huijgens, P Sonneveld, A A van de Loosdrecht, M Jongen-Lavrencic

Registry-linked trialAbstract readLetterComment
PubMed Publisher
In one paragraph

Article in Leukemia, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04806906 (A Phase 2, Monocentric, Pilot Study to Evaluate Safety and Efficacy of CC 486), which is not on this map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04806906 phase2completednot on this mapstarted 2021, after this paper: background citation

A Phase 2, Monocentric, Pilot Study to Evaluate Safety and Efficacy of CC 486 (Oral Azacitidine) Plus Best Supportive Care as Maintenance of Response to sc Azacitidine in IPSS Higher Risk Elderly MDS Patients

TypeinterventionalSponsorUniversity of FlorenceRan2021 to 2025Enrolled11ConditionsMDS, CMMLArmsCC-486
3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Clinical activity, pharmacokinetics, and pharmacodynamics of oral hypomethylating agents for myelodysplastic syndromes/neoplasms and acute myeloid leukemia: A multidisciplinary review.Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners · 2024
    Review
  2. Article
  3. Observational
  4. Article
  5. Article
  6. Review
  7. Article
  8. Integrating patient-centered factors in the risk assessment of MDS.Hematology. American Society of Hematology. Education Program · 2019
    Review
  9. In MDS, is higher risk higher reward?Hematology. American Society of Hematology. Education Program · 2019
    Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

A G DinmohamedDepartment of Hematology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.
Y van NordenClinical Trial Center-HOVON Data Center, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.
O VisserNetherlands Comprehensive Cancer Organisation, Utrecht, The Netherlands.
E F M PosthumaDepartment of Internal Medicine, Reinier de Graaf Group, Delft, The Netherlands.
P C HuijgensNetherlands Comprehensive Cancer Organisation, Utrecht, The Netherlands.
P SonneveldDepartment of Hematology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.
A A van de LoosdrechtDepartment of Hematology, Cancer Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands.
M Jongen-LavrencicDepartment of Hematology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antimetabolites, AntineoplasticAzacitidineFemaleHumansMaleMyelodysplastic SyndromesAntimetabolites, AntineoplasticAzacitidine

Identifiers

PMID26369829

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.