Evidence map›Paper›PMID 26369700›Full record

ArticleOncotarget2015

Mitochondrial transport of protoporphyrinogen IX in erythroid cells.

Yvette Y Yien, Alessa R Ringel, Barry H Paw

Open access · diamondAbstract readEditorial
In one paragraph

Article in Oncotarget, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. The role of ClpX in erythropoietic protoporphyria.Hematology, transfusion and cell therapy
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Yvette Y YienHematology Division, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, USA.
Alessa R RingelHematology Division, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, USA.
Barry H PawHematology Division, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, USA.
Harvard University · USBrigham and Women's Hospital · US

Funding

TRANSCRIPTION FACTOR GATA-1 IN TERMINAL ERYTHROID DEVELOPMENTP01HL032262 · NHLBI · CHILDREN'S HOSPITAL BOSTON · PI YIEN, YVETTE Y · 1985 to 2021
$38.9M
Frascati: mitochondrial transporter and erythropoiesisR01DK070838 · NIDDK · BRIGHAM AND WOMEN'S HOSPITAL · PI PAW, BARRY H · 2007 to 2011
$1.8M
Mechanism and Function of TMEM14 proteins in vertebrate heme synthesisK01DK106156 · NIDDK · UNIVERSITY OF DELAWARE · PI YIEN, YVETTE Y · 2015 to 2019
$793k
NHLBI NIH HHS P01 HL032262NIDDK NIH HHS K01 DK106156NIDDK NIH HHS R01 DK070838
6 · The paper itself

Abstract

Comment on: Yien Y, et al. TMEM14C is required for erythroid mitochondrial heme metabolism. J. Clin. Invest. 2014; 124:4294-4304.

Indexed as

AnimalsBiological TransportErythroid CellsHemeHomeostasisHumansMiceMitochondriaProtoporphyrinsSequence Analysis, RNAZebrafishHemeprotoporphyrinogenProtoporphyrinsheme synthesisporphyrin transportersTmem14c

Identifiers

PMID26369700
PMCPMC4673221
OpenAlexW2229431321

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.