Trial reportBMC musculoskeletal disorders2015
Patient-Reported Outcomes Measurement Information System (PROMIS) instruments among individuals with symptomatic knee osteoarthritis: a cross-sectional study of floor/ceiling effects and construct validity.
Trial report in BMC musculoskeletal disorders, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 44 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Tai Chi and Physical Therapy for Knee Osteoarthritis
Regional Nerve Blocks to Improve Analgesia and Recovery in Older Adults Undergoing Spinal Fusion
Who cites it
44 citing papers in PubMed, 3 syntheses or guidelines pooled it, 105 citations in OpenAlex.
- PROMIS Versus Legacy Patient-Reported Outcome Measures for Sports Medicine Patients Undergoing Arthroscopic Knee, Shoulder, and Hip Interventions: A Systematic Review.The Iowa orthopaedic journal · 2021Pooled it
- Injury-related variation in patient-reported outcome after musculoskeletal trauma: a systematic review.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2020Pooled it
- Focused Evidence Review: Psychometric Properties of Patient-Reported Outcome Measures for Chronic Musculoskeletal Pain.Journal of general internal medicine · 2018Pooled it
- Patient-Reported Outcomes Measurement Information System (PROMIS) Instruments: Reliability and Validity in Veterans Following Orthopedic Surgery.Evaluation & the health professions · 2020Trial
- Healthcare service utilization and work-related productivity in reflexology intervention for advanced breast cancer women.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019Trial
- Detecting functional change in response to exercise in knee osteoarthritis: a comparison of two computerized adaptive tests.BMC musculoskeletal disorders · 2018Trial
- Responsiveness and Minimally Important Differences for 4 Patient-Reported Outcomes Measurement Information System Short Forms: Physical Function, Pain Interference, Depression, and Anxiety in Knee Osteoarthritis.The journal of pain · 2017Trial
- Reliability and Construct Validity of the Patient-Reported Outcomes Measurement Information System (PROMIS) Instruments in Women with Fibromyalgia.Pain medicine (Malden, Mass.) · 2017Trial
- Quantitative Understanding of Advanced Novel Imaging Techniques for Fasciitis and Biosignature Yield (Quantify): Protocol for a Cross-Sectional Diagnostic Study.JMIR research protocols · 2026Article
- Patterns of Psychological Distress of Chinese Elderly Cancer Patients: A Latent Profile Analysis.Nursing open · 2025Article
- Article
- Validation of PROMIS anxiety item bank computer adaptive test among patients with heart failure.Frontiers in cardiovascular medicine · 2025Article
- Application of the implementation research logic model for evaluating a framework for disseminating arthritis-appropriate evidence-based interventions.Frontiers in health services · 2025Article
- What does routine depression screening in the ambulatory orthopedic clinic teach us? Results from nearly 60,000 patient encounters.Journal of orthopaedics · 2024Article
- Surgical healing beyond the scalpel: exploring the impact of depressive symptoms on functional recovery in total knee arthroplasty patients.Journal of orthopaedic surgery and research · 2023Article
- Measurement properties of PROMIS short forms for pain and function in patients receiving knee arthroplasty.Journal of patient-reported outcomes · 2023Article
- Personal factors and baseline function in patients undergoing non-operative management for chronic hip-related groin pain: a cross-sectional study.BMJ open sport & exercise medicine · 2023Article
- Prescribing Fewer Opioids After Rotator Cuff Repair and Anterior Cruciate Ligament Reconstruction Lowers Opioid Consumption Without Impacting Patient-Reported Pain Scores.Arthroscopy, sports medicine, and rehabilitation · 2022Article
- Assessment of Outcomes After Multisurface Osteochondral Allograft Transplantations in the Knee.Orthopaedic journal of sports medicine · 2022Article
- Prospective, Single-blind, Randomized Controlled Trial to Evaluate the Effectiveness of a Digital Exercise Therapy Application Compared With Conventional Physical Therapy for the Treatment of Nonoperative Knee Conditions.Archives of rehabilitation research and clinical translation · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundThe psychometric properties of Patient Reported Outcomes Measurement Information System (PROMIS) instruments have been explored in a number of general and clinical samples. No study, however, has evaluated the psychometric function of these measures in individuals with symptomatic knee osteoarthritis (KOA). The aim of this project was to evaluate the construct (structural) validity and floor/ceiling effects of four PROMIS measures in this population.
methodsWe conducted a secondary analysis of baseline data from a randomized trial comparing Tai Chi and physical therapy. Participants completed four PROMIS static short-form instruments (i.e., Anxiety, Depression, Physical Function, and Pain Interference) as well as six well-validated (legacy) measures that assess pain, function, and psychological health. We calculated descriptive statistics and percentages of participants scoring the minimum (floor) and maximum (ceiling) possible scores for PROMIS and legacy measures. We also estimated the association between PROMIS scores and scores on legacy measures using Spearman's rank correlations coefficients.
resultsData from 204 participants were analyzed. Mean age of the sample was 60 years; 70% were female. The PROMIS Anxiety and Depression had floor effects with 17 and 24% of participants scoring the minimum, respectively. PROMIS Anxiety and Depression scores had strongest associations with general mental health, including stress (Perceived Stress Scale, r ≥ 0.65) and depression (Beck Depression Index-II, r = 0.70). PROMIS Pain Interference scores correlated most strongly with measures of whole body pain (Short-Form 36 Bodily Pain, r = -0.73) and physical health (Short-Form 36 Physical-Component Summary, r = -0.73); their correlations were lower with other legacy measures, including with the WOMAC knee-specific pain (r = 0.47). PROMIS Physical Function scores had stronger associations with scores on the Short-Form 36 Physical Function (r = 0.79) than with scores on other legacy measures.
conclusionThe four PROMIS static-short forms performed well among individuals with symptomatic knee osteoarthritis as evidenced in correlations with legacy measures. PROMIS Anxiety and Depression target general mental health (e.g., stress, depression), and PROMIS Pain Interference and Physical Function static-short forms target whole-body outcomes among participants with symptomatic knee osteoarthritis. Floor effects in the PROMIS Anxiety and Depression scores should be considered if needing to distinguish among patients with very low levels of these outcomes.
trial registrationClinicaltrials.gov NCT01258985. Registered 10 December 2010.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.