ArticleHuman brain mapping2015
Development of the brain's structural network efficiency in early adolescence: A longitudinal DTI twin study.
Article in Human brain mapping, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
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Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it, 79 citations in OpenAlex.
- The stability of cognitive abilities: A meta-analytic review of longitudinal studies.Psychological bulletin · 2024Pooled it
- Developmental and aging changes in brain network switching dynamics revealed by EEG phase synchronization.PLoS computational biology · 2026Article
- White matter microstructure changes across the lifespan: a meta-analysis of longitudinal diffusion MRI studies.bioRxiv : the preprint server for biology · 2025Article
- Longitudinal development of the human white matter structural connectome and its association with brain transcriptomic and cellular architecture.Communications biology · 2023Article
- Maximizing the value of twin studies in health and behaviour.Nature human behaviour · 2023Review
- Transdiagnostic profiles of behaviour and communication relate to academic and socioemotional functioning and neural white matter organisation.Journal of child psychology and psychiatry, and allied disciplines · 2023Article
- Structural networking of the developing brain: from maturation to neurosurgical implications.Frontiers in neuroanatomy · 2023Review
- Deviations from normative brain white and gray matter structure are associated with psychopathology in youth.Developmental cognitive neuroscience · 2022Article
- Cognitive dysfunction in schizophrenia: An expert group paper on the current state of the art.Schizophrenia research. Cognition · 2022Review
- Multivariate Genetic Structure of Externalizing Behavior and Structural Brain Development in a Longitudinal Adolescent Twin Sample.International journal of molecular sciences · 2022Article
- Multisite Harmonization of Structural DTI Networks in Children: An A-CAP Study.Frontiers in neurology · 2022Article
- Adverse childhood experiences and fronto-subcortical structures in the developing brain.Frontiers in psychiatry · 2022Article
- Application of Magnetic Resonance DTI Technique in Evaluating the Effect of Postoperative Exercise Rehabilitation.Journal of healthcare engineering · 2022Article
- Estimating the Heritability of Developmental Change in Neural Connectivity, and Its Association With Changing Symptoms of Attention-Deficit/Hyperactivity Disorder.Biological psychiatry · 2021Article
- Neurocognitive reorganization between crystallized intelligence, fluid intelligence and white matter microstructure in two age-heterogeneous developmental cohorts.Developmental cognitive neuroscience · 2020Article
- Time-lagged associations between cognitive and cortical development from childhood to early adulthood.Developmental psychology · 2019Article
- The development of brain network hubs.Developmental cognitive neuroscience · 2019Review
- The development of brain white matter microstructure.NeuroImage · 2018Review
- Diffusion MRI of white matter microstructure development in childhood and adolescence: Methods, challenges and progress.Developmental cognitive neuroscience · 2018Review
- Children's academic attainment is linked to the global organization of the white matter connectome.Developmental science · 2018Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The brain is a network and our intelligence depends in part on the efficiency of this network. The network of adolescents differs from that of adults suggesting developmental changes. However, whether the network changes over time at the individual level and, if so, how this relates to intelligence, is unresolved in adolescence. In addition, the influence of genetic factors in the developing network is not known. Therefore, in a longitudinal study of 162 healthy adolescent twins and their siblings (mean age at baseline 9.9 [range 9.0-15.0] years), we mapped local and global structural network efficiency of cerebral fiber pathways (weighted with mean FA and streamline count) and assessed intelligence over a three-year interval. We find that the efficiency of the brain's structural network is highly heritable (locally up to 74%). FA-based local and global efficiency increases during early adolescence. Streamline count based local efficiency both increases and decreases, and global efficiency reorganizes to a net decrease. Local FA-based efficiency was correlated to IQ. Moreover, increases in FA-based network efficiency (global and local) and decreases in streamline count based local efficiency are related to increases in intellectual functioning. Individual changes in intelligence and local FA-based efficiency appear to go hand in hand in frontal and temporal areas. More widespread local decreases in streamline count based efficiency (frontal cingulate and occipital) are correlated with increases in intelligence. We conclude that the teenage brain is a network in progress in which individual differences in maturation relate to level of intellectual functioning.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.