ArticleJournal of epidemiology and global health2016
Epidemiology of invasive pneumococcal disease in Saudi Arabian children younger than 5years of age.
Article in Journal of epidemiology and global health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pneumococcal disease in children in the Middle East and Northern Africa: A systematic literature review of clinical burden, serotype distribution, and vaccination programs.Human vaccines & immunotherapeutics · 2024Pooled it
- Strengthening regional surveillance: MenMap Network's year 1 findings on bacterial meningitis in Jordan, Egypt, and Iraq (2023-2024).IJID regions · 2026Article
- Pneumococcal Infection and Vaccination-Related Knowledge, Attitudes and Practices Among Saudi Residents.Pathogens (Basel, Switzerland) · 2025Observational
- Invasive pneumococcal disease in the Gulf region: a narrative review of incidence, burden, and vaccine strategies.Frontiers in public health · 2025Review
- Machine Learning Strategies for Preoperative PJI Diagnosis: Integrative Analysis of Serum and Synovial Fluid Markers.Journal of inflammation research · 2025Article
- Article
- Emerging pneumococcal serotypes in Iraq: scope for improved vaccine development.F1000Research · 2023Review
- Review
- Trends in antimicrobial susceptibility patterns in King Fahad Medical City, Riyadh, Saudi Arabia.Saudi medical journal · 2019Article
- Phenotypic and molecular study of pneumococci causing respiratory tract infections. A 3-year prospective cohort.Saudi medical journal · 2017Article
- Optimizing the benefits of pneumococcal vaccination in the Kingdom of Saudi Arabia.Annals of thoracic medicineArticle
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study evaluated the incidence, serotype distribution, and antimicrobial susceptibility of invasive pneumococcal disease (IPD) in Saudi Arabian children. This multicenter, prospective, clinical surveillance study included children under 5years of age, residents of one of the seven study health areas, who were brought to a study hospital with suspicion of IPD. Bacterial isolates from sterile site samples, collected less than 24h after hospital visit/admission, were identified, serotyped, and tested for antibiotic susceptibility. Between June 2007 and January 2009, 631 episodes of suspected IPD were recorded, and 623 were included in the analysis. One child (0.2%) had previously received one dose of a pneumococcal vaccine. Forty-seven episodes were positive for Streptococcus pneumoniae and three for Haemophilus influenzae. The incidence of confirmed IPD cases was estimated to be 2.5-21.6 per 100,000 children (<5years). Among the 46 S. pneumoniae isolates serotyped and tested for antibiotic susceptibility, the most common serotypes were 5 and 23F (20% each), 6B (17%), and 1 and 14 (11% each). Sixty-three percent of isolates were multidrug-resistant. Vaccination of Saudi Arabian children with expanded-coverage conjugate pneumococcal vaccines containing serotypes 1 and 5 could have a substantial impact to prevent IPD in this population.
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