Evidence map›Paper›PMID 26368661›Full record

ArticleEnvironment international2015

Use of pooled samples to assess human exposure to parabens, benzophenone-3 and triclosan in Queensland, Australia.

A L Heffernan, C Baduel, L M L Toms, A M Calafat, X Ye, P Hobson, S Broomhall, J F Mueller

Open access · greenAbstract read
In one paragraph

Article in Environment international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 101 citations in OpenAlex.

  1. Pooled it
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  12. Article
  13. Evaluation of Parabens and Bisphenol A Concentration Levels in Wild Bat Guano Samples.International journal of environmental research and public health · 2023
    Article
  14. Article
  15. Article
  16. Genomic markers for the biological responses of Triclosan stressed hatchlings of Labeo rohita.Environmental science and pollution research international · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

A L HeffernanNational Research Centre for Environmental Toxicology, University of Queensland, Brisbane, QLD, Australia. Electronic address: amy.heffernan@uqconnect.edu.au.
C BaduelNational Research Centre for Environmental Toxicology, University of Queensland, Brisbane, QLD, Australia. Electronic address: c.baduel@uq.edu.au.
L M L TomsQueensland University of Technology, School of Public Health and Social Work and Institute of Health and Biomedical Innovation, Brisbane, QLD, Australia. Electronic address: leisamaree.toms@qut.edu.au.
A M CalafatCenters for Disease Control and Prevention, Atlanta, GA, USA. Electronic address: aic7@cdc.gov.
X YeCenters for Disease Control and Prevention, Atlanta, GA, USA. Electronic address: xay5@cdc.gov.
P HobsonSullivan Nicolaides Pathology Taringa, QLD, Australia. Electronic address: Peter_Hobson@snp.com.au.
S BroomhallThe Department of Environment, Canberra, ACT, Australia. Electronic address: Sara.Broomhall@environment.gov.au.
J F MuellerNational Research Centre for Environmental Toxicology, University of Queensland, Brisbane, QLD, Australia. Electronic address: j.mueller@uq.edu.au.
The University of Queensland · AUCenters for Disease Control and Prevention · USDepartment of Agriculture, Water and the Environment · AUQueensland University of Technology · AUSullivan Nicolaides Pathology · AU

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

Parabens, benzophenone-3 and triclosan are common ingredients used as preservatives, ultraviolet radiation filters and antimicrobial agents, respectively. Human exposure occurs through consumption of processed food and use of cosmetics and consumer products. The aim of this study was to provide a preliminary characterisation of exposure to selected personal care product chemicals in the general Australian population. De-identified urine specimens stratified by age and sex were obtained from a community-based pathology laboratory and pooled (n=24 pools of 100). Concentrations of free and total (sum of free plus conjugated) species of methyl, ethyl, propyl and butyl paraben, benzophenone-3 and triclosan were quantified using isotope dilution tandem mass spectrometry; with geometric means 232, 33.5, 60.6, 4.32, 61.5 and 87.7ng/mL, respectively. Age was inversely associated with paraben concentration, and females had concentrations approximately two times higher than males. Total paraben and benzophenone-3 concentrations are significantly higher than reported worldwide, and the average triclosan concentration was more than one order of magnitude higher than in many other populations. This study provides the first data on exposure of the general Australian population to a range of common personal care product chemical ingredients, which appears to be prevalent and warrants further investigation.

Indexed as

AdolescentAdultAgedAge FactorsBenzophenonesChildChild, PreschoolCosmeticsEnvironmental ExposureFemaleHumansMaleMiddle AgedParabensPreservatives, PharmaceuticalQueenslandBenzophenonesCosmeticsoxybenzoneParabensPreservatives, PharmaceuticalSunscreening AgentsTriclosanBiomonitoringChildrenParabensPersonal care productsPopulation monitoringUrine

Identifiers

PMID26368661
PMCPMC5537729
OpenAlexW1911267016

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.