Trial reportPloS one2015
Adverse Events during Bowel Preparation and Colonoscopy in Patients with Acute Lower Gastrointestinal Bleeding Compared with Elective Non-Gastrointestinal Bleeding.
Trial report in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed.
- Comparison of PEG-Based and Non-PEG Bowel Preparation for Emergency Colonoscopy in Acute Lower Gastrointestinal Bleeding: A Real-World Cohort Study with IPTW Analysis.Digestive diseases and sciences · 2026Article
- Evidence-based, cost-effective management of lower gastrointestinal bleeding. An algorithm of the journal of trauma and acute care surgery emergency general surgery algorithms work group.The journal of trauma and acute care surgery · 2026Article
- 1 versus 2 L PEG/Asc for bowel preparation in patients with hematochezia: a multicenter, prospective, randomized, non-inferiority study.Therapeutic advances in gastroenterology · 2026Article
- Characteristics and outcomes of patients undergoing esophagogastroduodenoscopy in Gaza strip hospitals: a retrospective study.BMC gastroenterology · 2025Article
- Early Versus Late Bowel Preparation for Suspected Acute Diverticular Bleeding: A Retrospective Study.Cureus · 2025Article
- Association of blood group O with a recurrent risk for acute lower gastrointestinal bleeding from a multicenter cohort study.Scientific reports · 2024Article
- Article
- Colonoscopy: Preparation and Potential Complications.Diagnostics (Basel, Switzerland) · 2022Article
- Endoscopic direct clipping versus indirect clipping for colonic diverticular bleeding: A large multicenter cohort study.United European gastroenterology journal · 2022Article
- Novel frontiers of agents for bowel cleansing for colonoscopy.World journal of gastroenterology · 2021Review
- Role of endoscopy in acute gastrointestinal bleeding in real clinical practice: An evidence-based review.World journal of gastrointestinal endoscopy · 2019Review
- Article
- Patients' comorbidities reduce the clinical value of emergency colonoscopy: results of a retrospective cohort study.Endoscopy international open · 2017Article
- Comparison of claims data on hospitalization rates and repeat procedures in patients receiving a bowel preparation prior to colonoscopy.SAGE open medicine · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere are limited data on the safety of colonoscopy in patients with lower gastrointestinal bleeding (LGIB). We examined the various adverse events associated with colonoscopy in acute LGIB compared with non-GIB patients.
methodsEmergency hospitalized LGIB patients (n = 161) and age- and gender-matched non-GIB controls (n = 161) were selected. Primary outcomes were any adverse events during preparation and colonoscopy procedure. Secondary outcomes were five bowel preparation-related adverse events--hypotension, systolic blood pressure <100 mmHg, volume overload, vomiting, aspiration pneumonia and loss of consciousness--and four colonoscopy-related adverse events--including hypotension, perforation, cerebrocardiovascular events and sepsis.
resultsDuring bowel preparation, 16 (9%) LGIB patients experienced an adverse event. None of the LGIB patients experienced volume overload, aspiration pneumonia or loss of consciousness; however, 12 (7%) had hypotension and 4 (2%) vomited. There were no significant differences in the five bowel preparation-related adverse events between LGIB and non-GIB patients. During colonoscopy, 25 (15%) LGIB patients experienced an adverse event. None LGIB patient had perforation or sepsis; however, 23 (14%) had hypotension and 2 (1%) experienced a cerebrocardiovascular event. There was no significant difference in the four colonoscopy-related adverse events between LGIB and non-GIB patients. In addition, no significant difference in any of the nine adverse events was found among subgroups: patients aged ≥65 years, those with comorbidities, and those with antithrombotic drug use.
conclusionsAdverse events in bowel preparation and colonoscopy among acute LGIB patients were low. No significant difference was found in adverse events between LGIB and non-GIB patients. These adverse events were also low in elderly LGIB patients, as well as in those with co-morbidities and antithrombotic drug use, suggesting that colonoscopy performed during acute LGIB did not increase adverse events.
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