Trial reportPloS one2015
Prevalence of Sarcopenia and Its Relationship with Sites of Fragility Fractures in Elderly Chinese Men and Women.
Trial report in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 4 syntheses or guidelines pooled it, 78 citations in OpenAlex.
- Sarcopenia in distal radius fractures: systematic review of the literature and current findings.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2020Pooled it
- Sarcopenia and its association with falls and fractures in older adults: A systematic review and meta-analysis.Journal of cachexia, sarcopenia and muscle · 2019Pooled it
- The relationship between sarcopenia and fragility fracture-a systematic review.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2019Pooled it
- Association of sarcopenia and fractures in community-dwelling older adults: a systematic review and meta-analysis of cohort studies.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018Pooled it
- DXA-derived hip shape is associated with hip fracture: a longitudinal study of 38 123 UK Biobank participants.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2026Article
- Impact of probiotic, prebiotic, and synbiotic supplementation on the gut microbiome in older adults with sarcopenia, obesity, and sarcopenic obesity.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026Review
- Body Mass Index Changes and Femur Fracture Risk in Parkinson's Disease: National Cohort Study.Journal of cachexia, sarcopenia and muscle · 2025Article
- Handgrip strength as a predictor of 1‑year mortality after hip fracture surgery in the Colombian Andes Mountains.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025Article
- Changes in lumbar muscle diffusion tensor indices with age.BJR open · 2024Article
- Association between Serum Oxytocin, Bone Mineral Density and Body Composition in Chinese Adult Females.Medicina (Kaunas, Lithuania) · 2022Article
- Effect of Resistance Training Combined with Beta-Hydroxy-Beta-Methylbutyric Acid Supplements in Elderly Patients with Sarcopenia after Hip Replacement.Orthopaedic surgery · 2022Article
- The feasibility and acceptability of assessing and managing sarcopenia and frailty among older people with upper limb fracture.Age and ageing · 2022Article
- Muscle plays a more superior role than fat in bone homeostasis: A cross-sectional study of old Asian people.Frontiers in endocrinology · 2022Article
- Interactive effect of sarcopenia and falls on vertebral osteoporotic fracture in patients with rheumatoid arthritis.Archives of osteoporosis · 2021Article
- Metabolic Shock in Elderly Pertrochanteric or Intertrochanteric Surgery. Comparison of Three Surgical Methods. Is there a Much Safer?Romanian journal of anaesthesia and intensive care · 2020Article
- Association between Health Indicators and Health-Related Quality of Life according to Physical Activity of Older Women.Healthcare (Basel, Switzerland) · 2020Article
- Diagnosis, Treatment and Prevention of Sarcopenia in Hip Fractured Patients: Where We Are and Where We Are Going: A Systematic Review.Journal of clinical medicine · 2020Review
- Comparing Longitudinal Sarcopenia Trends by Definitions Across Men and Women After Hip Fracture.Journal of the American Geriatrics Society · 2020Observational
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Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveSarcopenia might be associated with bone fragility in elderly individuals. This study aimed to investigate the prevalence of sarcopenia and its association with fragility fracture sites in elderly Chinese patients.
methodsPatients (322 men and 435 women) aged 65-94 years and with a history of fragility fractures in the ankle, wrist, vertebrae or hip, and healthy men (n = 1263) and women (n = 1057) aged 65-92 years without a history of fractures were enrolled. Whole-body dual energy X-ray absorptiometry was used to analyze skeletal muscle mass index (SMI), fat mass and bone mineral density. Sarcopenia was defined as SMI less than two standard deviations below the mean of a young reference group.
resultsSarcopenia occurrence varied with fracture location. Sarcopenia was more common in females with vertebral and hip fractures and in men with hip and ankle fractures than in the non-fracture group). Sarcopenia was significantly more prevalent in men with wrist, hip and ankle fractures than in women. SMI was correlated with BMD in different fracture groups. Logistic regression analyses revealed that lower SMI was associated with an increased risk of hip fracture both in men and women and ankle fracture in men. DISCUSSION: Sarcopenia may be an independent risk factor for hip and ankle fractures in men, and for hip fractures in women.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.