Evidence map›Paper›PMID 26367827›Full record

ArticleApplied optics2015

In vivo tissue injury mapping using optical coherence tomography based methods.

Utku Baran, Yuandong Li, Ruikang K Wang

Abstract read
In one paragraph

Article in Applied optics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Research and application advances in rehabilitation assessment of stroke.Journal of Zhejiang University. Science. B · 2022
    Review
  3. Article
  4. Dynamic capillary stalls in reperfused ischemic penumbra contribute to injury: A hyperacute role for neutrophils in persistent traffic jams.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021
    Article
  5. Article
  6. Cerebral edema detectionNeurophotonics · 2019
    Article
  7. Review
  8. LongitudinalJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2019
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Potential use of OCT-based microangiography in clinical dermatology.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2016
    Article
  16. Article
  17. Optical Coherence Tomography for Brain Imaging and Developmental Biology.IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Utku Baran
Yuandong Li
Ruikang K Wang

Funding

OPTICAL MICROANGIOGRAHY OF CEREBROVASCULAR PERFUSIONR01HL093140 · NHLBI · UNIVERSITY OF WASHINGTON · PI WANG, RUIKANG · 2008 to 2017
$4.2M
Label-free optical imaging of 3D structural and functional microcirculationsR01EB009682 · NIBIB · UNIVERSITY OF WASHINGTON · PI WANG, RUIKANG · 2009 to 2012
$1.7M
NHLBI NIH HHS R01 HL093140NHLBI NIH HHS R01HL093140NIBIB NIH HHS R01 EB009682NIBIB NIH HHS R01EB009682
6 · The paper itself

Abstract

An injury causes changes in the optical attenuation coefficient (OAC) of a light beam traveling inside a tissue. We report a method called tissue injury mapping (TIM), which utilizes a noninvasive in vivo optical coherence tomography approach to generate an OAC and microvascular map of the injured tissue. Using TIM, the infarct region development in a mouse cerebral cortex during a stroke is visualized. Moreover, we demonstrate the changes in human facial skin structure and microvasculature during an acne lesion development from initiation to scarring. The results indicate that TIM may be used to aid in the characterization and the treatment of various diseases by enabling a high-resolution detection of tissue structural and microvascular changes.

Indexed as

AlgorithmsAngiographyAnimalsBrainCerebral CortexDiagnostic ImagingFaceHumansImage Processing, Computer-AssistedImaging, Three-DimensionalLightMiceMicrocirculationMicrovesselsScattering, RadiationSkin

Identifiers

PMID26367827
PMCPMC4570269

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.