Evidence map›Paper›PMID 26367243›Full record

ReviewExpert review of molecular diagnostics2015

Molecular detection and point-of-care testing in Ebola virus disease and other threats: a new global public health framework to stop outbreaks.

Gerald J Kost, William Ferguson, Anh-Thu Truong, Jackie Hoe, Daisy Prom, Arirat Banpavichit, Surin Kongpila

Open access · greenAbstract readReview
In one paragraph

Review in Expert review of molecular diagnostics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Health-Care Access during the Ebola Virus Epidemic in Liberia.The American journal of tropical medicine and hygiene · 2017
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Gerald J Kost
William Fergusona University of California, Davis, USA.
Anh-Thu Truonga University of California, Davis, USA.
Jackie Hoea University of California, Davis, USA.
Daisy Proma University of California, Davis, USA.
Arirat Banpavichita University of California, Davis, USA.
Surin Kongpilaa University of California, Davis, USA.
University of California, Davis · USNorth-West State Technical University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ultrahigh sensitivity and specificity assays that detect Ebola virus disease or other highly contagious and deadly diseases quickly and successfully upstream in Spatial Care Paths™ can stop outbreaks from escalating into devastating epidemics ravaging communities locally and countries globally. Even had the WHO and CDC responded more quickly and not misjudged the dissemination of Ebola in West Africa and other world regions, mobile rapid diagnostics were, and still are, not readily available for immediate and definitive diagnosis, a stunning strategic flaw that needs correcting worldwide. This article strategizes point-of-care testing for diagnosis, triage, monitoring, recovery and stopping outbreaks in the USA and other countries; reviews Ebola molecular diagnostics, summarizes USA FDA emergency use authorizations and documents why they should not be stop-gaps; and reduces community risk from internal and external infectious disease threats by enabling public health at points of need.

Indexed as

Point-of-Care SystemsCivil DefenseDisease OutbreaksHemorrhagic Fever, EbolaHumansInternational CooperationKnowledge BasesMolecular Diagnostic TechniquesSensitivity and SpecificityEbolaEbola diagnostic centeremergency use authorizationfacilitated-access self-testingpoint-of-carepublic health resilienceultrahigh sensitivityultrahigh specificity

Identifiers

PMID26367243
PMCPMC7103715
OpenAlexW2104195839

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.