Evidence map›Paper›PMID 26367017›Full record

ArticleJournal of traumatic stress2015

Temporal Associations Among Chronic PTSD Symptoms in U.S. Combat Veterans.

Susan Doron-LaMarca, Barbara L Niles, Daniel W King, Lynda A King, Anica Pless Kaiser, Michael J Lyons

Abstract read
In one paragraph

Article in Journal of traumatic stress, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Does exposure exacerbate symptoms in veterans with PTSD and alcohol use disorder?Psychological trauma : theory, research, practice and policy · 2021
    Trial
  3. Trial
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  10. Complementary and integrative interventions for PTSD.European journal of psychotraumatology · 2023
    Article
  11. Observational
  12. Parallel process modeling of posttraumatic stress disorder symptoms and alcohol use severity in returning veterans.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2020
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  13. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Susan Doron-LaMarcaBehavioral Science Division, National Center for PTSD, VA Boston Healthcare System, and Boston University School of Medicine, Boston, Massachusetts, USA.
Barbara L NilesBehavioral Science Division, National Center for PTSD, VA Boston Healthcare System, and Boston University School of Medicine, Boston, Massachusetts, USA.
Daniel W KingNational Center for PTSD, VA Boston Healthcare System, Department of Psychology, Boston University, and Department of Psychiatry, Boston University School of Medicine, Boston, Massachusetts, USA.
Lynda A KingNational Center for PTSD, VA Boston Healthcare System, Department of Psychology, Boston University, and Department of Psychiatry, Boston University School of Medicine, Boston, Massachusetts, USA.
Anica Pless KaiserBehavioral Science Division, National Center for PTSD, VA Boston Healthcare System, and Boston University School of Medicine, Boston, Massachusetts, USA.
Michael J LyonsDepartment of Psychological and Brain Sciences, Boston University, Boston, Massachusetts, USA.

Funding

1/4-Stimulant and Risperidone for Youth with Severe Physical AggressionR01MH077907 · NIMH · OHIO STATE UNIVERSITY · PI AMAN, MICHAEL GEORGE · 2008 to 2011
$1.9M
New Longitudinal Methods for Trauma ResearchR01MH068626 · NIMH · BOSTON UNIVERSITY MEDICAL CAMPUS · PI KING, DANIEL W · 2004 to 2006
$871k
Intramural VA VA999999NIMH NIH HHS R01 MH068626NIMH NIH HHS R01 MH077907NIMH NIH HHS R01MH68626NIMH NIH HHS R03MH77907
6 · The paper itself

Abstract

The present study examined fluctuation over time in symptoms of posttraumatic stress disorder (PTSD) among 34 combat veterans (28 with diagnosed PTSD, 6 with subclinical symptoms) assessed every 2 weeks for up to 2 years (range of assessments = 13-52). Temporal relationships were examined among four PTSD symptom clusters (reexperiencing, avoidance, emotional numbing, and hyperarousal) with particular attention to the influence of hyperarousal. Multilevel cross-lagged random coefficients autoregression for intensive time series data analyses were used to model symptom fluctuation decades after combat experiences. As anticipated, hyperarousal predicted subsequent fluctuations in the 3 other PTSD symptom clusters (reexperiencing, avoidance, emotional numbing) at subsequent 2-week intervals (rs = .45, .36, and .40, respectively). Additionally, emotional numbing influenced later reexperiencing and avoidance, and reexperiencing influenced later hyperarousal (rs = .44, .40, and .34, respectively). These findings underscore the important influence of hyperarousal. Furthermore, results indicate a bidirectional relationship between hyperarousal and reexperiencing as well as a possible chaining of symptoms (hyperarousal → emotional numbing → reexperiencing → hyperarousal) and establish potential internal, intrapersonal mechanisms for the maintenance of persistent PTSD symptoms. Results suggested that clinical interventions targeting hyperarousal and emotional numbing symptoms may hold promise for PTSD of long duration.

Indexed as

ArousalVietnam ConflictBostonChronic DiseaseHumansMaleProspective StudiesSeverity of Illness IndexSickness Impact ProfileStress Disorders, Post-TraumaticTime FactorsUnited StatesVeterans

Identifiers

PMID26367017
PMCPMC6785199

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.