ArticlePloS one2015
Anoxic Biodegradation of Isosaccharinic Acids at Alkaline pH by Natural Microbial Communities.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 20 citations in OpenAlex.
- Microbial degradation of citrate mediates sealing of cement cracks under anaerobic conditions relevant to radioactive waste disposal.Npj Materials degradation · 2025Article
- Extremophilic microbial metabolism and radioactive waste disposal.Extremophiles : life under extreme conditions · 2023Review
- The evolution of alkaliphilic biofilm communities in response to extreme alkaline pH values.MicrobiologyOpen · 2022Article
- Microbial Degradation of Citric Acid in Low Level Radioactive Waste Disposal: Impact on Biomineralization Reactions.Frontiers in microbiology · 2021Article
- Enhanced microbial degradation of irradiated cellulose under hyperalkaline conditions.FEMS microbiology ecology · 2020Article
- Hydrogenotrophic Methanogenesis Under Alkaline Conditions.Frontiers in microbiology · 2020Article
- Microbial Degradation of Cellulosic Material and Gas Generation: Implications for the Management of Low- and Intermediate-Level Radioactive Waste.Frontiers in microbiology · 2019Article
- The biogeochemical fate of nickel during microbial ISA degradation; implications for nuclear waste disposal.Scientific reports · 2018Article
- The Impact of Alkaliphilic Biofilm Formation on the Release and Retention of Carbon Isotopes from Nuclear Reactor Graphite.Scientific reports · 2018Article
- Adsorption of aliphatic polyhydroxy carboxylic acids on gibbsite: pH dependency and importance of adsorbate structure.Environmental sciences Europe · 2018Article
- Whole-Genome Sequence of the Anaerobic Isosaccharinic Acid Degrading Isolate, Macellibacteroides fermentans Strain HH-ZS.Genome biology and evolution · 2017Article
- Floc Formation Reduces the pH Stress Experienced by Microorganisms Living in Alkaline Environments.Applied and environmental microbiology · 2017Article
- Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
One design concept for the long-term management of the UK's intermediate level radioactive wastes (ILW) is disposal to a cementitious geological disposal facility (GDF). Under the alkaline (10.0<pH>13.0) anoxic conditions expected within a GDF, cellulosic wastes will undergo chemical hydrolysis. The resulting cellulose degradation products (CDP) are dominated by α- and β-isosaccharinic acids (ISA), which present an organic carbon source that may enable subsequent microbial colonisation of a GDF. Microcosms established from neutral, near-surface sediments demonstrated complete ISA degradation under methanogenic conditions up to pH 10.0. Degradation decreased as pH increased, with β-ISA fermentation more heavily influenced than α-ISA. This reduction in degradation rate was accompanied by a shift in microbial population away from organisms related to Clostridium sporosphaeroides to a more diverse Clostridial community. The increase in pH to 10.0 saw an increase in detection of Alcaligenes aquatilis and a dominance of hydrogenotrophic methanogens within the Archaeal population. Methane was generated up to pH 10.0 with acetate accumulation at higher pH values reflecting a reduced detection of acetoclastic methanogens. An increase in pH to 11.0 resulted in the accumulation of ISA, the absence of methanogenesis and the loss of biomass from the system. This study is the first to demonstrate methanogenesis from ISA by near surface microbial communities not previously exposed to these compounds up to and including pH 10.0.
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