Evidence map›Paper›PMID 26366747›Full record

ArticleAngewandte Chemie (International ed. in English)2015

Development of Enantioselective Palladium-Catalyzed Alkene Carboalkoxylation Reactions for the Synthesis of Tetrahydrofurans.

Brett A Hopkins, Zachary J Garlets, John P Wolfe

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Enantio- and Regioselective Palladium(II)-Catalyzed Dioxygenation of (Aza-)Alkenols.Angewandte Chemie (International ed. in English) · 2021
    Article
  6. Article
  7. Article
  8. Article
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Brett A HopkinsDepartment of Chemistry, University of Michigan, 930. N. University Ave, Ann Arbor, MI 48109-1055 (USA).
Zachary J GarletsDepartment of Chemistry, University of Michigan, 930. N. University Ave, Ann Arbor, MI 48109-1055 (USA).
John P WolfeDepartment of Chemistry, University of Michigan, 930. N. University Ave, Ann Arbor, MI 48109-1055 (USA). jpwolfe@umich.edu.

Funding

New Alkene Difunctionalization Reactions for Organic SynthesisR01GM098314 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WOLFE, JOHN P · 2011 to 2014
$1.1M
NIGMS NIH HHS GM098314NIGMS NIH HHS R01 GM098314
6 · The paper itself

Abstract

The Pd-catalyzed coupling of γ-hydroxyalkenes with aryl bromides affords enantiomerically enriched 2-(arylmethyl)tetrahydrofuran derivatives in good yield and up to 96:4 e.r. This transformation was achieved through the development of a new TADDOL/2-arylcyclohexanol-derived chiral phosphite ligand. The transformations are effective with an array of different aryl bromides, and can be used for the preparation of products bearing quaternary stereocenters.

Indexed as

AlkenesCatalysisFuransMolecular StructureOrganometallic CompoundsPalladiumStereoisomerismAlkenesFuransOrganometallic CompoundsPalladiumasymmetric catalysisenantioselective synthesisheterocyclespalladium

Identifiers

PMID26366747
PMCPMC4711365

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.