Evidence map›Paper›PMID 26366639›Full record

Trial reportAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2016

Psychosocial Predictors of Mortality Following Lung Transplantation.

P J Smith, J A Blumenthal, E P Trulock, K E Freedland, R M Carney, R D Davis, B M Hoffman, S M Palmer

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 2 pooled it
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 88 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Telehealth interventions to improve outcomes in lung transplant recipients: Primary results of the INSPIRE-III randomized clinical trial.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2025
    Trial
  4. Article
  5. Article
  6. Article
  7. Psychosocial challenges with transplantation.Current opinion in pulmonary medicine · 2026
    Review
  8. Article
  9. Barriers to Immunosuppressant Medication Adherence in Thoracic Transplant Recipients: Initial Findings.International journal of environmental research and public health · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Consensus document for the selection of lung transplant candidates: An update from the International Society for Heart and Lung Transplantation.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2021
    Article
  20. The role of palliative care in lung transplantation.Journal of thoracic disease · 2021
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

P J SmithDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC.
J A BlumenthalDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC.
E P TrulockWashington University School of Medicine, St. Louis, MO.
K E FreedlandWashington University School of Medicine, St. Louis, MO.
R M CarneyWashington University School of Medicine, St. Louis, MO.
R D DavisDepartment of Surgery, Duke University Medical Center, Durham, NC.
B M HoffmanDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC.
S M PalmerDepartment of Medicine, Duke University Medical Center, Durham, NC.
Duke University Hospital · USWashington University in St. Louis · USDuke Medical Center · US

Funding

TELEPHONE STRESS MANAGEMENT FOR LUNG TRANSPLANT PATIENTSR01HL065503 · NHLBI · DUKE UNIVERSITY · PI BLUMENTHAL, JAMES A · 2000 to 2012
$6.9M
NHLBI NIH HHS HL 065503NHLBI NIH HHS R01 HL065503
6 · The paper itself

Abstract

Lung transplantation has become an increasingly common treatment for patients with end-stage lung disease. Few studies have examined psychosocial risk factors for mortality in transplant recipients, despite evidence suggesting that elevated levels of negative affect are associated with greater mortality following major cardiac surgery. We therefore examined the relationship between negative affect early after lung transplantation and long-term survival in a sample of 132 lung transplant recipients (28 cystic fibrosis, 64 chronic obstructive pulmonary disease, 26 idiopathic pulmonary fibrosis, 14 other) followed for up to 13.5 years (median 7.4 years) following transplantation. Patients underwent both medical and psychosocial assessments 6 months following transplantation, which included the Beck Depression Inventory-II (BDI-II), Spielberger Anxiety Inventory, and General Health Questionnaire (GHQ). Over the course of follow-up, 80 (61%) participants died. Controlling for demographic factors, native lung disease, disease severity, family income, education level, social support, and frequency of posttransplant rejection, elevated symptoms of depression (BDI-II: HR = 1.31, p = 0.011) and distress (GHQ: HR = 1.28, p = 0.003) were associated with increased mortality. Higher levels of depression and general distress, but not anxiety, measured 6 months following lung transplantation are associated with increased mortality, independent of background characteristics and medical predictors.

Indexed as

Postoperative ComplicationsAnxietyFemaleFollow-Up StudiesGraft RejectionGraft SurvivalHumansLung TransplantationMajor Depressive DisorderMaleMiddle AgedPrognosisRisk FactorsTransplant Recipients

Identifiers

PMID26366639
PMCPMC4830128
OpenAlexW1820125608

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.