ArticleCurrent epidemiology reports2015
Developmental Programming: Priming Disease Susceptibility for Subsequent Generations.
Article in Current epidemiology reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A systematic review of historic neighborhood redlining and contemporary health outcomes.Public health · 2025Pooled it
- Neighborhood socioeconomic conditions and depression: a systematic review and meta-analysis.Social psychiatry and psychiatric epidemiology · 2015Pooled it
- Infant and Toddler Consumption of Sweetened and Unsweetened Lipid Nutrient Supplements After 2-Week Home Repeated Exposures.The Journal of nutrition · 2021Trial
- Early-life exposure to residential black carbon and childhood cardiometabolic health.Environmental research · 2023Article
- Complexity and interplay of faced adversities and perceived health and well-being in highly vulnerable pregnant women-the Mothers of Rotterdam program.BMC public health · 2023Article
- Maternal High-Fat Diet and Offspring Hypertension.International journal of molecular sciences · 2022Review
- Socio-economic determinants of healthcare costs in early life: a register-based study in the Netherlands.International journal for equity in health · 2022Article
- Health Agency and Perfectionism: The Case of Perinatal Health Inequalities.Public health ethics · 2021Article
- Article
- The Contribution of Neighborhood Socioeconomic Disadvantage to Depressive Symptoms Over the Course of Adult Life: A 32-Year Prospective Cohort Study.American journal of epidemiology · 2020Article
- Maternal prepregnancy BMI and size at birth: race/ethnicity-stratified, within-family associations in over 500,000 siblings.Annals of epidemiology · 2020Article
- Social Determinants of Placental Health and Future Disease Risks for Babies.Obstetrics and gynecology clinics of North America · 2020Review
- High-fat diet from parental generation exaggerates body and adipose tissue weights in pregnant offspring.PloS one · 2020Article
- Maternal prenatal stress phenotypes associate with fetal neurodevelopment and birth outcomes.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Malprogramming of Hepatic Lipid Metabolism due to Excessive Early Cholesterol Exposure in Adult Progeny.Molecular nutrition & food research · 2019Article
- A Framework to Address Challenges in Communicating the Developmental Origins of Health and Disease.Current environmental health reports · 2016Article
- Framing Strategies to Avoid Mother-Blame in Communicating the Origins of Chronic Disease.American journal of public health · 2016Article
- Developmental Origins, Epigenetics, and Equity: Moving Upstream.Maternal and child health journal · 2016Review
- From fatalism to mitigation: A conceptual framework for mitigating fetal programming of chronic disease by maternal obesity.Preventive medicine · 2015Review
- The programming of cardiovascular disease.Journal of developmental origins of health and disease · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Racial and/or ethnic minorities carry the highest burden of many adverse health outcomes intergenerationally We propose a paradigm in which developmental programming exacerbates the effects of racial patterning of adverse environmental conditions, thereby contributing to health disparity persistence. Evidence that developmental programming induces a heightened response to adverse exposures ("second hits") encountered later in life is considered. We evaluated the evidence for the second hit phenomenon reported in animal and human studies from three domains (air, stress, nutrition). Original research including a gestational exposure and a childhood or adulthood second hit exposure was reviewed. Evidence from animal studies suggest that prenatal exposure to
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.