Evidence map›Paper›PMID 26366230›Full record

ArticleCellular and molecular bioengineering2015

Nanopatterned Human iPSC-based Model of a Dystrophin-Null Cardiomyopathic Phenotype.

Jesse Macadangdang, Xuan Guan, Alec S T Smith, Rachel Lucero, Stefan Czerniecki, Martin K Childers, David L Mack, Deok-Ho Kim

Abstract read
In one paragraph

Article in Cellular and molecular bioengineering, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Gene Editing and Human iPSCs in Cardiovascular and Metabolic Diseases.Advances in experimental medicine and biology · 2023
    Article
  7. Genome Editing and Pathological Cardiac Hypertrophy.Advances in experimental medicine and biology · 2023
    Article
  8. Article
  9. Article
  10. ESC working group on cardiac cellular electrophysiology position paper: relevance, opportunities, and limitations of experimental models for cardiac electrophysiology research.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2021
    Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Nanopatterned Nafion microelectrode arrays forAdvanced functional materials · 2020
    Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jesse MacadangdangDepartment of Bioengineering, University of Washington, Seattle, WA, USA ; Institute of Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA, USA.
Xuan GuanDepartment of Physiology and Pharmacology, School of Medicine, Wake Forest University Health Sciences, Winston-Salem, NC, USA ; Department of Rehabilitation Medicine, University of Washington, Seattle, WA, USA ; Institute of Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA, USA.
Alec S T SmithDepartment of Bioengineering, University of Washington, Seattle, WA, USA.
Rachel LuceroDepartment of Bioengineering, University of Washington, Seattle, WA, USA.
Stefan CzernieckiDepartment of Rehabilitation Medicine, University of Washington, Seattle, WA, USA ; Institute of Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA, USA.
Martin K ChildersDepartment of Rehabilitation Medicine, University of Washington, Seattle, WA, USA ; Institute of Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA, USA.
David L MackDepartment of Rehabilitation Medicine, University of Washington, Seattle, WA, USA ; Institute of Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA, USA.
Deok-Ho KimDepartment of Bioengineering, University of Washington, Seattle, WA, USA ; Institute of Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA, USA.

Funding

Vector Research Resource CoreU54AR065139 · NIAMS · UNIVERSITY OF WASHINGTON · PI CHAMBERLAIN, JEFFREY S · 2014 to 2017
$6.3M
Bioengineering Cardiovascular Training GrantT32EB001650 · NIBIB · UNIVERSITY OF WASHINGTON · PI REGNIER, MICHAEL · 2004 to 2019
$3.6M
Nanopatterned 3D Vascularized Functional Muscle PatchR21AR064395 · NIAMS · UNIVERSITY OF WASHINGTON · PI KIM, DEOK-HO · 2014 to 2015
$421k
NIAMS NIH HHS R21 AR064395NIAMS NIH HHS U54 AR065139NIBIB NIH HHS T32 EB001650
6 · The paper itself

Abstract

Human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs) offer unprecedented opportunities to study inherited heart conditions

Indexed as

Cytoskeletal AlignmentDuchenne muscular dystrophyFRAPStem Cell Derived Cardiomyocytes

Identifiers

PMID26366230
PMCPMC4564135

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.