ArticlePostepy dermatologii i alergologii2015
Insulin resistance in severe acne vulgaris.
Article in Postepy dermatologii i alergologii, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
26 citing papers in PubMed, 60 citations in OpenAlex.
- The Association of Acne Vulgaris and Disease Severity With Serum Amyloid A1 and Insulin Levels.Journal of cosmetic dermatology · 2026Article
- Exposome involvement in the development of acne vulgaris.Frontiers in immunology · 2026Review
- New Perspectives on Nutraceutical Insulin Sensitizing Agents in the Treatment of Psoriasis and Other Dermatological Diseases.International journal of molecular sciences · 2025Review
- Investigating metabolic syndrome markers and body mass index changes in patients with acne vulgaris treated with isotretinoin: A prospective study.Journal of cosmetic dermatology · 2024Article
- In severe acne vulgaris, TNF-α gene variants are connected to increased TNF-α gene expression and insulin resistance.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024Article
- Metformin Therapy for Acne Vulgaris: A Meta-Analysis.Pharmaceuticals (Basel, Switzerland) · 2024Review
- Oily fish reduces the risk of acne by lowering fasting insulin levels: A Mendelian randomization study.Food science & nutrition · 2024Article
- Article
- Exploring the Metabolic and Endocrine Preconditioning Associated with Thyroid Disorders: Risk Assessment and Association with Acne Severity.International journal of molecular sciences · 2024Article
- Significance of host antimicrobial peptides in the pathogenesis and treatment of acne vulgaris.Frontiers in immunology · 2024Review
- Insulin Resistance in Patients with Acne Vulgaris.Biomedicines · 2023Article
- Article
- Article
- Insulin and the sebaceous gland function.Frontiers in physiology · 2023Review
- Insulin Resistance and Acne: The Role of Metformin as Alternative Therapy in Men.Pharmaceuticals (Basel, Switzerland) · 2022Review
- Insulin resistance in the course of acne - literature review.Postepy dermatologii i alergologii · 2022Review
- Potential roles of gut microbial tryptophan metabolites in the complex pathogenesis of acne vulgaris.Frontiers in microbiology · 2022Review
- Skin disease related to metabolic syndrome in women.International journal of women's dermatology · 2019Review
- Metabolic Syndrome and Skin Diseases.Frontiers in endocrinology · 2019Review
- Clinical, Biochemical, and Hormonal Associations in Female Patients with Acne: A Study and Literature Review.The Journal of clinical and aesthetic dermatology · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAcne vulgaris is a pilosebaceous gland disease that usually affects people from puberty to young adulthood. It is seen especially on the face, neck, trunk and arms. Its severity differs from patient to patient and its pathogenesis is multifactorial. The main pathogenic factors of acne are high sebaceous gland secretion, follicular hyperproliferation, high androgen effects, propionibacterium acnes colonization and inflammation. Diet is always thought a probable reason for acne and many studies are done about acne and diet.
aimTo determine the effect of insulin resistance in severe acne vulgaris. MATERIAL AND
methodsTwo hundred and forty-three acne vulgaris patients and 156 healthy controls were enrolled into the study. The blood levels of insulin and glucose were measured. Homeostasis Model Assessment (HOMA) Index was calculated. The values were compared with the control group.
resultsAll of the patients were in the severe acne group according to their scores on the global acne scoring scale. While fasting blood glucose levels were not different between the groups (p > 0.05, 82.91 ±9.76 vs. 80.26 ±8.33), the fasting insulin levels were significantly higher in the patient group than in the control group (p < 0.001, 14.01 ±11.94 vs. 9.12 ±3.53). Additionally, there was a highly significant difference between the patient and control groups in terms of HOMA values (p < 0.001, 2.87 ±2.56 vs. 1.63 ±0.65).
conclusionsThese results suggest that insulin resistance may have a role in the pathogenesis of acne.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.