Evidence map›Paper›PMID 26365173›Full record

ReviewProgress in neurobiology2015

Active Inference, homeostatic regulation and adaptive behavioural control.

Giovanni Pezzulo, Francesco Rigoli, Karl Friston

Abstract readReview
In one paragraph

Review in Progress in neurobiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 224 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
224citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

224 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  8. Acoustic voice analysis of women with migraine.Arquivos de neuro-psiquiatria · 2026
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164 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Giovanni PezzuloInstitute of Cognitive Sciences and Technologies, National Research Council, Rome, Italy. Electronic address: giovanni.pezzulo@istc.cnr.it.
Francesco RigoliWellcome Trust, UCL, London, UK.
Karl FristonWellcome Trust, UCL, London, UK.

Funding

Wellcome Trust 088130Wellcome Trust 088130/Z/09/ZWellcome Trust 091593
6 · The paper itself

Abstract

We review a theory of homeostatic regulation and adaptive behavioural control within the Active Inference framework. Our aim is to connect two research streams that are usually considered independently; namely, Active Inference and associative learning theories of animal behaviour. The former uses a probabilistic (Bayesian) formulation of perception and action, while the latter calls on multiple (Pavlovian, habitual, goal-directed) processes for homeostatic and behavioural control. We offer a synthesis these classical processes and cast them as successive hierarchical contextualisations of sensorimotor constructs, using the generative models that underpin Active Inference. This dissolves any apparent mechanistic distinction between the optimization processes that mediate classical control or learning. Furthermore, we generalize the scope of Active Inference by emphasizing interoceptive inference and homeostatic regulation. The ensuing homeostatic (or allostatic) perspective provides an intuitive explanation for how priors act as drives or goals to enslave action, and emphasises the embodied nature of inference.

Indexed as

Models, NeurologicalModels, PsychologicalAnimalsAssociation LearningBehaviorBrainHomeostasisHumansActive InferenceAdaptive controlHomeostatic regulationModel-based controlModel-free controlPavlovian control

Identifiers

PMID26365173
PMCPMC4779150

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.