Evidence map›Paper›PMID 26364987›Full record

ArticleVirulence2015

The influence of bacterial interaction on the virulence of Cryptococcus neoformans.

Sanjiveeni Dhamgaye, Gerald L Murray, Anton Y Peleg

Open access · goldAbstract readEditorialComment
In one paragraph

Article in Virulence, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Frontiers in cellular and infection microbiology · 2022
    Article
  2. Interactions between invasive fungi and symbiotic bacteria.World journal of microbiology & biotechnology · 2020
    Review
  3. The Spectrum of Interactions betweenJournal of fungi (Basel, Switzerland) · 2019
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Sanjiveeni Dhamgayea Department of Microbiology ; Monash University ; Melbourne , Australia.
Gerald L Murraya Department of Microbiology ; Monash University ; Melbourne , Australia.
Anton Y Pelega Department of Microbiology ; Monash University ; Melbourne , Australia.
Monash University · AUCentral Clinical Hospital · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microbes exist in complex communities in the environment. The interaction between fungi, such as the opportunistic pathogen Cryptococcus neoformans, and antagonistic environmental bacteria, such as Acinetobacter spp., may influence fungal evolution through the production of fungal defence mechanisms that inadvertently enhance fungal pathogenicity. Such changes include alteration of biofilm formation and increased capsule production. The molecular mechanisms responsible for such changes, both from a bacterial and fungal point of view, are of great interest to understanding the evolution of pathogenicity. Additionally, further elucidation of the stability of the induced changes in C. neoformans, and the impacts of these change on the disease-causing potential of this fungus, is of great interest.

Indexed as

Microbial InteractionsAcinetobacter baumanniiCryptococcus neoformansAcinetobacter baumanniiC. neoformansevolutionpolymicrobial interactionvirulence

Identifiers

PMID26364987
PMCPMC4720233
OpenAlexW2139676876

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.