ArticleAngewandte Chemie (International ed. in English)2015
Electronic Olfactory Sensor Based on A. mellifera Odorant-Binding Protein 14 on a Reduced Graphene Oxide Field-Effect Transistor.
Article in Angewandte Chemie (International ed. in English), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Recent Advances and Unaddressed Challenges in Biomimetic Olfactory- and Taste-Based Biosensors: Moving Towards Integrated, AI-Powered, and Market-Ready Sensing Systems.Sensors (Basel, Switzerland) · 2025Review
- Olfactory binding proteins: a review across the Insecta.Frontiers in zoology · 2025Review
- Exploring Scent Distinction with Polymer Brush Arrays.ACS applied polymer materials · 2025Article
- Biosensors for Odor Detection: A Review.Biosensors · 2023Review
- Adaptive Peptide Molecule as the Promising Highly-Efficient Gas-Sensor Material: In Silico Study.Sensors (Basel, Switzerland) · 2023Article
- Fabrication of MoSMicromachines · 2023Article
- Article
- Progress in the Development of Detection Strategies Based on Olfactory and Gustatory Biomimetic Biosensors.Biosensors · 2022Review
- Laser-Induced Graphene-Functionalized Field-Effect Transistor-Based Biosensing: A Potent Candidate for COVID-19 Detection.IEEE transactions on nanobioscience · 2022Review
- A Hybrid Microfluidic Electronic Sensing Platform for Life Science Applications.Micromachines · 2022Article
- An Overview of Artificial Olfaction Systems with a Focus on Surface Plasmon Resonance for the Analysis of Volatile Organic Compounds.Biosensors · 2021Review
- Responses of the Pheromone-Binding Protein of the Silk MothSensors (Basel, Switzerland) · 2021Article
- Bio-Inspired Strategies for Improving the Selectivity and Sensitivity of Artificial Noses: A Review.Sensors (Basel, Switzerland) · 2020Review
- Biosensors to Monitor Water Quality Utilizing Insect Odorant-Binding Proteins as Detector Elements.Biosensors · 2019Article
- Effects of point mutations in the binding pocket of the mouse major urinary protein MUP20 on ligand affinity and specificity.Scientific reports · 2019Article
- Protein- and Peptide-Based Biosensors in Artificial Olfaction.Trends in biotechnology · 2018Review
- Odorant-Binding Proteins as Sensing Elements for Odour Monitoring.Sensors (Basel, Switzerland) · 2018Review
- From Protein Features to Sensing Surfaces.Sensors (Basel, Switzerland) · 2018Review
- Membrane protein-based biosensors.Journal of the Royal Society, Interface · 2018Review
- Genotyping and Bio-Sensing Chemosensory Proteins in Insects.Sensors (Basel, Switzerland) · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An olfactory biosensor based on a reduced graphene oxide (rGO) field-effect transistor (FET), functionalized by the odorant-binding protein 14 (OBP14) from the honey bee (Apis mellifera) has been designed for the in situ and real-time monitoring of a broad spectrum of odorants in aqueous solutions known to be attractants for bees. The electrical measurements of the binding of all tested odorants are shown to follow the Langmuir model for ligand-receptor interactions. The results demonstrate that OBP14 is able to bind odorants even after immobilization on rGO and can discriminate between ligands binding within a range of dissociation constants from K(d)=4 μM to K(d)=3.3 mM. The strongest ligands, such as homovanillic acid, eugenol, and methyl vanillate all contain a hydroxy group which is apparently important for the strong interaction with the protein.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.