Evidence map›Paper›PMID 26364747›Full record

ReviewLab on a chip2015

Review: in vitro microvessel models.

Max I Bogorad, Jackson DeStefano, Johan Karlsson, Andrew D Wong, Sharon Gerecht, Peter C Searson

Abstract readReview
In one paragraph

Review in Lab on a chip, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers.

0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

76 citing papers in PubMed.

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16 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Max I BogoradInstitute for Nanobiotechnology (INBT), 100 Croft Hall, Johns Hopkins University, 3400 North Charles Street, Baltimore, MD 21218, Maryland 21218, USA. searson@jhu.edu.
Jackson DeStefanoInstitute for Nanobiotechnology (INBT), 100 Croft Hall, Johns Hopkins University, 3400 North Charles Street, Baltimore, MD 21218, Maryland 21218, USA. searson@jhu.edu.
Johan KarlssonInstitute for Nanobiotechnology (INBT), 100 Croft Hall, Johns Hopkins University, 3400 North Charles Street, Baltimore, MD 21218, Maryland 21218, USA. searson@jhu.edu.
Andrew D WongInstitute for Nanobiotechnology (INBT), 100 Croft Hall, Johns Hopkins University, 3400 North Charles Street, Baltimore, MD 21218, Maryland 21218, USA. searson@jhu.edu.
Sharon GerechtDepartment of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, Maryland 21218, USA.
Peter C SearsonInstitute for Nanobiotechnology (INBT), 100 Croft Hall, Johns Hopkins University, 3400 North Charles Street, Baltimore, MD 21218, Maryland 21218, USA. searson@jhu.edu and Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, Maryland 21218, USA.

Funding

T32: Predoctoral and Postdoctoral Training Program in Nanotechnology for Cancer ResearchT32CA153952 · NCI · JOHNS HOPKINS UNIVERSITY · PI Denis Wirtz · 2015 to 2026
$3.5M
Mechanisms of cerebrovascular barrier dysfunction caused by APP and PSEN1 mutations and amyloid beta exposureR01NS106008 · NINDS · JOHNS HOPKINS UNIVERSITY · PI SEARSON, PETER C · 2019 to 2023
$1.9M
T-32 NIH Postdoctoral Training Program in Nanotechnology for Cancer Medicine NTCMT32CA130840 · NCI · JOHNS HOPKINS UNIVERSITY · PI WIRTZ, DENIS · 2008 to 2012
$1.2M
NCI NIH HHS T32 CA130840NCI NIH HHS T32 CA153952NINDS NIH HHS R01 NS106008
6 · The paper itself

Abstract

A wide range of perfusable microvessel models have been developed, exploiting advances in microfabrication, microfluidics, biomaterials, stem cell technology, and tissue engineering. These models vary in complexity and physiological relevance, but provide a diverse tool kit for the study of vascular phenomena and methods to vascularize artificial organs. Here we review the state-of-the-art in perfusable microvessel models, summarizing the different fabrication methods and highlighting advantages and limitations.

Indexed as

Microfluidic Analytical TechniquesModels, BiologicalAnimalsEndothelium, VascularHumans

Identifiers

PMID26364747
PMCPMC9397147

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.