Evidence map›Paper›PMID 26364615›Full record

ReviewOncogene2015

Emerging strategies for cancer immunoprevention.

J C Roeser, S D Leach, F McAllister

Open access · bronzeAbstract readReview
In one paragraph

Review in Oncogene, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
1.9field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 52 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Consideration of SHP-1 as a Molecular Target for Tumor Therapy.International journal of molecular sciences · 2023
    Review
  7. The STAT3-Regulated Autophagy Pathway in Glioblastoma.Pharmaceuticals (Basel, Switzerland) · 2023
    Review
  8. [Activation of JAK/STAT in ovarian high-grade serous cancers and its prognostic significance].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2023
    Article
  9. Review
  10. Mouse Models to Study Secondary Cancer Prevention.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  11. Article
  12. Targets and Strategies for Cancer Immunoprevention.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  13. Review
  14. (20S) Ginsenoside Rh2 Inhibits STAT3/VEGF Signaling by Targeting Annexin A2.International journal of molecular sciences · 2021
    Article
  15. CD63Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020
    Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Stat3 is indispensable for damage-induced crypt regeneration but not for Wnt-driven intestinal tumorigenesis.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

J C RoeserDepartment of Oncology. Johns Hopkins University. Maryland, MD, USA.
S D LeachThe David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
F McAllisterDepartment of Clinical Cancer Prevention. The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Johns Hopkins University · USMemorial Sloan Kettering Cancer Center · USThe University of Texas MD Anderson Cancer Center · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
Zebrafish CoreP01CA134292 · NCI · JOHNS HOPKINS UNIVERSITY · PI LEACH, STEVEN D · 2009 to 2013
$7.4M
NCI NIH HHS P01 CA134292
6 · The paper itself

Abstract

The crucial role of the immune system in the formation and progression of tumors has been widely accepted. On one hand, the surveillance role of the immune system plays an important role in endogenous tumor prevention, but on the other hand, in some special circumstances such as in chronic inflammation, the immune system can actually contribute to the formation and progression of tumors. In recent years, there has been an explosion of novel targeted immunotherapies for advanced cancers. In the present manuscript, we explore known and potential various types of cancer prevention strategies and focus on nonvaccine-based cancer preventive strategies targeting the immune system at the early stages of tumorigenesis.

Indexed as

ChemopreventionDendritic CellsHumansImmunotherapyInterleukin 1 Receptor Antagonist ProteinInterleukin-6 InhibitorsInterleukin-8Monitoring, ImmunologicNeoplasmsProgrammed Cell Death 1 ReceptorSTAT3 Transcription FactorTh17 CellsT-Lymphocytes, RegulatoryInterleukin 1 Receptor Antagonist ProteinInterleukin-6 InhibitorsInterleukin-8PDCD1 protein, humanProgrammed Cell Death 1 ReceptorSTAT3 Transcription Factor

Identifiers

PMID26364615
PMCPMC11073473
OpenAlexW2200775887

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.