ArticleTopics in spinal cord injury rehabilitation2015
Acute Cardiorespiratory and Metabolic Responses During Exoskeleton-Assisted Walking Overground Among Persons with Chronic Spinal Cord Injury.
Article in Topics in spinal cord injury rehabilitation, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
58 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Effects of robot-assisted gait training on cardiopulmonary function and lower extremity strength in individuals with spinal cord injury: A systematic review and meta-analysis.The journal of spinal cord medicine · 2024Pooled it
- Global research trends and hotspots of artificial intelligence research in spinal cord neural injury and restoration-a bibliometrics and visualization analysis.Frontiers in neurology · 2024Pooled it
- Overground robotic training effects on walking and secondary health conditions in individuals with spinal cord injury: systematic review.Journal of neuroengineering and rehabilitation · 2022Pooled it
- The Effects of Powered Exoskeleton Gait Training on Cardiovascular Function and Gait Performance: A Systematic Review.Sensors (Basel, Switzerland) · 2021Pooled it
- Sample sizes and statistical methods in interventional studies on individuals with spinal cord injury: A systematic review.Journal of evidence-based medicine · 2019Pooled it
- Robotic assisted gait as a tool for rehabilitation of individuals with spinal cord injury: a systematic review.Journal of neuroengineering and rehabilitation · 2017Pooled it
- Gait speed using powered robotic exoskeletons after spinal cord injury: a systematic review and correlational study.Journal of neuroengineering and rehabilitation · 2015Pooled it
- Safety assessment and feasibility of the TWIICE powered exoskeleton for assisted ambulation in individuals with spinal cord injury.Journal of neuroengineering and rehabilitation · 2025Trial
- Comparing walking with knee-ankle-foot orthoses and a knee-powered exoskeleton after spinal cord injury: a randomized, crossover clinical trial.Scientific reports · 2022Trial
- Energy cost and psychological impact of robotic-assisted gait training in people with spinal cord injury: effect of two different types of devices.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021Trial
- Exoskeleton-assisted walking improves pulmonary function and walking parameters among individuals with spinal cord injury: a randomized controlled pilot study.Journal of neuroengineering and rehabilitation · 2021Trial
- Trial
- Locomotor training using an overground robotic exoskeleton in long-term manual wheelchair users with a chronic spinal cord injury living in the community: Lessons learned from a feasibility study in terms of recruitment, attendance, learnability, performance and safety.Journal of neuroengineering and rehabilitation · 2018Trial
- Robotic Rehabilitation in Spinal Cord Injury: Neurophysiological Basis and Severity-Based Clinical Framework.Brain sciences · 2026Review
- A multidimensional evaluation of the Atalante exoskeleton as an assistive locomotion device for individuals with complete paraplegia: a prospective longitudinal study in a controlled environment.Journal of neuroengineering and rehabilitation · 2026Article
- Assistive Technologies for Individuals with a Disability from a Neurological Condition: A Narrative Review on the Multimodal Integration.Healthcare (Basel, Switzerland) · 2025Review
- Consumer views of functional electrical stimulation and robotic exoskeleton in SCI rehabilitation: A mini review.Artificial organs · 2025Review
- Epidural Stimulation and Resistance Training (REST-SCI) for Overground Locomotion After Spinal Cord Injury: Randomized Clinical Trial Protocol.Journal of clinical medicine · 2025Article
- Cardiac Function and Fatigue During Exoskeleton-Assisted Sit-to-Stand Maneuver and Walking in People with Stroke with Moderate to Severe Gait Disability: A Pilot Cross-Sectional Study.Sensors (Basel, Switzerland) · 2024Article
- Novel Design on Knee Exoskeleton with Compliant Actuator for Post-Stroke Rehabilitation.Sensors (Basel, Switzerland) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLower extremity robotic exoskeleton technology is being developed with the promise of affording people with spinal cord injury (SCI) the opportunity to stand and walk. The mobility benefits of exoskeleton-assisted walking can be realized immediately, however the cardiorespiratory and metabolic benefits of this technology have not been thoroughly investigated.
objectiveThe purpose of this pilot study was to evaluate the acute cardiorespiratory and metabolic responses associated with exoskeleton-assisted walking overground and to determine the degree to which these responses change at differing walking speeds.
methodsFive subjects (4 male, 1 female) with chronic SCI (AIS A) volunteered for the study. Expired gases were collected during maximal graded exercise testing and two, 6-minute bouts of exoskeleton-assisted walking overground. Outcome measures included peak oxygen consumption (V̇O2peak), average oxygen consumption (V̇O2avg), peak heart rate (HRpeak), walking economy, metabolic equivalent of tasks for SCI (METssci), walk speed, and walk distance.
resultsSignificant differences were observed between walk-1 and walk-2 for walk speed, total walk distance, V̇O2avg, and METssci. Exoskeleton-assisted walking resulted in %V̇O2peak range of 51.5% to 63.2%. The metabolic cost of exoskeleton-assisted walking ranged from 3.5 to 4.3 METssci.
conclusionsPersons with motor-complete SCI may be limited in their capacity to perform physical exercise to the extent needed to improve health and fitness. Based on preliminary data, cardiorespiratory and metabolic demands of exoskeleton-assisted walking are consistent with activities performed at a moderate intensity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.