ArticleAutism research : official journal of the International Society for Autism Research2016
Abnormal Brain Dynamics Underlie Speech Production in Children with Autism Spectrum Disorder.
Article in Autism research : official journal of the International Society for Autism Research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed.
- Paediatric magnetoencephalography and its role in neurodevelopmental disorders.The British journal of radiology · 2024Review
- Oromotor skills in autism spectrum disorder: A scoping review.Autism research : official journal of the International Society for Autism Research · 2023Article
- Atypical functional connectivity of temporal cortex with precuneus and visual regions may be an early-age signature of ASD.Molecular autism · 2023Article
- Altered engagement of the speech motor network is associated with reduced phonological working memory in autism.NeuroImage. Clinical · 2023Article
- Increased Intra-Subject Variability of Neural Activity During Speech Production in People with Autism Spectrum Disorder.Research in autism spectrum disorders · 2022Article
- The language network in autism: Atypical functional connectivity with default mode and visual regions.Autism research : official journal of the International Society for Autism Research · 2019Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
A large proportion of children with autism spectrum disorder (ASD) have speech and/or language difficulties. While a number of structural and functional neuroimaging methods have been used to explore the brain differences in ASD with regards to speech and language comprehension and production, the neurobiology of basic speech function in ASD has not been examined. Magnetoencephalography (MEG) is a neuroimaging modality with high spatial and temporal resolution that can be applied to the examination of brain dynamics underlying speech as it can capture the fast responses fundamental to this function. We acquired MEG from 21 children with high-functioning autism (mean age: 11.43 years) and 21 age- and sex-matched controls as they performed a simple oromotor task, a phoneme production task and a phonemic sequencing task. Results showed significant differences in activation magnitude and peak latencies in primary motor cortex (Brodmann Area 4), motor planning areas (BA 6), temporal sequencing and sensorimotor integration areas (BA 22/13) and executive control areas (BA 9). Our findings of significant functional brain differences between these two groups on these simple oromotor and phonemic tasks suggest that these deficits may be foundational and could underlie the language deficits seen in ASD.
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Registered trials
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