Evidence map›Paper›PMID 26363089›Full record

ReviewBiotechnology advances2015

Micro- and nanodevices integrated with biomolecular probes.

Yunus Alapan, Kutay Icoz, Umut A Gurkan

Abstract readReview
In one paragraph

Review in Biotechnology advances, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Shear dependent red blood cell adhesion in microscale flow.Integrative biology : quantitative biosciences from nano to macro · 2018
    Article
  7. Hypoxia-enhanced adhesion of red blood cells in microscale flow.Microcirculation (New York, N.Y. : 1994) · 2017
    Article
  8. Review
  9. Article
  10. Sickle cell disease biochip: a functional red blood cell adhesion assay for monitoring sickle cell disease.Translational research : the journal of laboratory and clinical medicine · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Yunus AlapanCase Biomanufacturing and Microfabrication Laboratory, Mechanical and Aerospace Engineering Department, Case Western Reserve University, Cleveland, OH 44106, USA.
Kutay IcozBio Micro/Nano Devices and Sensors Laboratory, Electrical and Electronics Engineering Department, Abdullah Gul University, Kayseri 38080, Turkey. Electronic address: kutay.icoz@agu.edu.tr.
Umut A GurkanCase Biomanufacturing and Microfabrication Laboratory, Mechanical and Aerospace Engineering Department, Case Western Reserve University, Cleveland, OH 44106, USA; Biomedical Engineering Department, Case Western Reserve University, Cleveland, OH 44106, USA; Department of Orthopaedics, Case Western Reserve University, Cleveland, OH 44106, USA; Advanced Platform Technology Center, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, OH 44106, USA. Electronic address: umut@case.edu.
Abdullah Gül University · TRCase Western Reserve University · USLouis Stokes Cleveland VA Medical Center · US

Funding

Clinical and Translational Science Collaborative of ClevelandUL1TR000439 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI KONSTAN, MICHAEL W. · 2012 to 2016
$50.0M
Doris Duke Charitable Foundation 2013126NCATS NIH HHS UL1 TR000439NCATS NIH HHS UL1TR000439
6 · The paper itself

Abstract

Understanding how biomolecules, proteins and cells interact with their surroundings and other biological entities has become the fundamental design criterion for most biomedical micro- and nanodevices. Advances in biology, medicine, and nanofabrication technologies complement each other and allow us to engineer new tools based on biomolecules utilized as probes. Engineered micro/nanosystems and biomolecules in nature have remarkably robust compatibility in terms of function, size, and physical properties. This article presents the state of the art in micro- and nanoscale devices designed and fabricated with biomolecular probes as their vital constituents. General design and fabrication concepts are presented and three major platform technologies are highlighted: microcantilevers, micro/nanopillars, and microfluidics. Overview of each technology, typical fabrication details, and application areas are presented by emphasizing significant achievements, current challenges, and future opportunities.

Indexed as

NanotechnologyBiosensing TechniquesHumansMicrofluidicsMolecular ProbesProteinsMolecular ProbesProteinsBiomoleculesBiosensingCell adhesionCell isolationMicrocantileversMicrofluidic channelsMicro/nanofabricationMicro/nanopillarsPoint-of-care diagnosisSurface functionalization

Identifiers

PMID26363089
PMCPMC4948648
OpenAlexW1625879877

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.