Evidence map›Paper›PMID 26362856›Full record

ArticleBMC research notes2015

Risk factors associated with mortality in patients infected with influenza A/H1N1 in Mexico.

Luis Alberto Mata-Marín, José Antonio Mata-Marín, Velasco Claudia Vásquez-Mota, Carla Ileana Arroyo-Anduiza, Jesús Enrique Gaytán-Martínez, Bulmaro Manjarrez-Téllez, Luis Alberto Ochoa-Carrera, Jorge Luis Sandoval-Ramírez

Abstract read
In one paragraph

Article in BMC research notes, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Severe acute respiratory infections (SARI) from influenza in adult patients in Chile: the experience of a sentinel hospital.Revista panamericana de salud publica = Pan American journal of public health · 2019
    Article
  9. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Luis Alberto Mata-MarínCardiology and Angiology Department, Herzzentrum am Klinikum Links der Weser, Senator-Weßling-Straße 1, 28277, Bremen, Germany. arzt.matamarin@yahoo.de.
José Antonio Mata-MarínInfectious Diseases Department, Hospital de Infectología, "La Raza" National Medical Center, IMSS, Mexico City, Mexico. jamatamarin@gmail.com.
Velasco Claudia Vásquez-MotaClinical Pathology Department, Hospital General, "La Raza" National Medical Center, IMSS, Mexico City, Mexico. cavasmove@hotmail.com.
Carla Ileana Arroyo-AnduizaCentral Blood Bank, "La Raza" National Medical Center, IMSS, Mexico City, Mexico. carlaileana@gmail.com.
Jesús Enrique Gaytán-MartínezInfectious Diseases Department, Hospital de Infectología, "La Raza" National Medical Center, IMSS, Mexico City, Mexico. jgaytanmtz@yahoo.com.mx.
Bulmaro Manjarrez-TéllezInfectious Diseases Department, Hospital de Infectología, "La Raza" National Medical Center, IMSS, Mexico City, Mexico. manjarrez23@yahoo.com.mx.
Luis Alberto Ochoa-CarreraImmunology and Infectious Diseases Research Unit, "La Raza" National Medical Center, IMSS, Mexico City, Mexico. qfbcarrera@hotmail.com.
Jorge Luis Sandoval-RamírezInfectious Diseases Department, Hospital de Infectología, "La Raza" National Medical Center, IMSS, Mexico City, Mexico. escribo_a_jorge@yahoo.com.mx.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInfluenza virus pandemics vary dramatically in their severity and mortality. Thus, it is very important to identify populations with high risks of developing severe illness to reduce mortality in future pandemics. The purpose was to determine the mortality-associated risk factors in hospitalized Mexican patients infected with influenza A/H1N1.

resultsThe risk factors associated with mortality were: male sex [odds ratio (OR) = 5.25, confidence interval (CI) = 1.22-28.95], medical attention delayed >3 days (OR = 9.9, CI = 1.51-64.52), anti-flu therapy delayed >3 days (OR = 10.0, CI = 1.07-93.43), admission to intensive care unit (ICU) (OR = 9.9, CI = 1.51-64.52) and creatinine levels >1.0 mg/dL when admitted to hospital (OR = 11.2, CI = 1.05-120.32). After adjusting for the effects of potentially confounding variables in a logistic regression model, delayed medical attention (OR = 13.91, CI = 1.09-41.42, p = 0.044) and ICU hospitalization (OR = 11.02, CI = 1.59-76.25, p = 0.015) were the only predictors of mortality.

conclusionEarly medical attention is essential for reducing the mortality risk in patients with influenza A/H1N1, while a requirement for ICU management increases the risk.

Indexed as

AdultFemaleHumansInfluenza A Virus, H1N1 SubtypeInfluenza, HumanMaleMexicoMiddle AgedMultivariate AnalysisRisk FactorsYoung Adult

Identifiers

PMID26362856
PMCPMC4566398

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.