Evidence map›Paper›PMID 26362690›Full record

Trial reportContemporary clinical trials2015

Long-term Exercise After Pulmonary Rehabilitation (LEAP): Design and rationale of a randomized controlled trial of Tai Chi.

Marilyn L Moy, Peter M Wayne, Daniel Litrownik, Douglas Beach, Elizabeth S Klings, Roger B Davis, Gloria Y Yeh

3 registry-linked trialsOpen access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Contemporary clinical trials, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 21 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 5 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01998724 nacompletednot on this map

Tai Chi After Pulmonary Rehabilitation in Patients With COPD: A Randomized Trial

TypeinterventionalSponsorBeth Israel Deaconess Medical CenterRan2012 to 2018Enrolled90ConditionsChronic Obstructive Pulmonary Disease (COPD)ArmsTai Chi, Group Walking
NCT03131752 naunknown statusnot on this mapstarted 2017, after this paper: background citation

Early Pulmonary Rehabilitation With Elastic Resistance in Exacerbated COPD Patients

TypeinterventionalSponsorUniversidade Federal de Sao CarlosRan2017 to 2019Enrolled38ConditionsChronic Obstructive Pulmonary DiseaseArmsElastic Resistance Intervention in Exacerbated Patients
NCT04019301 naunknown statusnot on this mapstarted 2019, after this paper: background citation

Caring for Caregivers With Mind-body Exercise

TypeinterventionalSponsorUniversity of HoustonRan2019 to 2022Enrolled47ConditionsCaregiver Distress, Physical Function, Quality of LifeArmsBaduanjin Qigong, Community-based, Baduanjin Qigong, Internet-based
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 5 syntheses or guidelines pooled it, 37 citations in OpenAlex.

  1. Pooled it
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  5. Health benefits of tai chi: What is the evidence?Canadian family physician Medecin de famille canadien · 2016
    Pooled it
  6. Trial
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  8. Review
  9. Review
  10. Article
  11. The Positive Role of Tai Chi in Responding to the COVID-19 Pandemic.International journal of environmental research and public health · 2021
    Article
  12. Article
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  15. Review
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  20. Canadian family physician Medecin de famille canadien · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Marilyn L MoyPulmonary and Critical Care Medicine Section, Department of Medicine, Veterans Administration Boston Healthcare System, Boston, MA, USA. Electronic address: marilyn.moy@va.gov.
Peter M WayneOsher Center for Integrative Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA,USA; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA. Electronic address: pwayne@partners.org.
Daniel LitrownikDivision of General Medicine and Primary Care, Department of Medicine, Beth Israel Deaconess Medical Center, Brookline, MA, USA. Electronic address: dlitrown@bidmc.harvard.edu.
Douglas BeachDivision of Pulmonary, Sleep and Critical Care Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA. Electronic address: dbeach@bidmc.harvard.edu.
Elizabeth S KlingsThe Pulmonary Center, Boston University School of Medicine, Boston, MA, USA. Electronic address: klingon@bu.edu.
Roger B DavisDivision of General Medicine and Primary Care, Department of Medicine, Beth Israel Deaconess Medical Center, Brookline, MA, USA. Electronic address: rdavis@bidmc.harvard.edu.
Gloria Y YehDivision of General Medicine and Primary Care, Department of Medicine, Beth Israel Deaconess Medical Center, Brookline, MA, USA. Electronic address: gyeh@hms.harvard.edu.
Beth Israel Deaconess Medical Center · USBoston University · USBrigham and Women's Hospital · USVA Boston Healthcare System · US

Funding

Tai Chi after Pulmonary Rehabilitation in Patients with COPD: A Randomized TrialR01AT006358 · NCCIH · BETH ISRAEL DEACONESS MEDICAL CENTER · PI MOY, MARILYN L., YEH, GLORIA Y · 2012 to 2016
$3.0M
NCCIH NIH HHS R01 AT006358NCCIH NIH HHS R01AT006358
6 · The paper itself

Abstract

backgroundPersons with chronic obstructive pulmonary disease (COPD) have reduced exercise capacity and levels of physical activity. Supervised, facility-based pulmonary rehabilitation programs improve exercise capacity and reduce dyspnea, but novel long-term strategies are needed to maintain the benefits gained. Mind-body modalities such as Tai Chi which combine aerobic activity, coordination of breathing, and cognitive techniques that alleviate the physical inactivity, dyspnea, and anxiety and depression that are the hallmarks of COPD are promising strategies. METHODS/

designWe have designed a randomized controlled study to examine whether Tai Chi will maintain exercise capacity in persons with COPD who have recently completed a supervised pulmonary rehabilitation program, compared to standard care. The primary outcome is 6-min walk test distance at 6 months. Secondary outcomes include health-related quality of life, dyspnea, mood, occurrence of acute exacerbations, engagement in physical activity, exercise self-efficacy, and exercise adherence. Simultaneously, we are conducting a pilot study of group walking. We will enroll 90 persons who will be randomized to one of three arms in a 2:2:1 ratio: Tai Chi, standard care, or group-based walking. DISCUSSION: The Long-term Exercise After Pulmonary Rehabilitation (LEAP) study is a novel and clinically relevant trial. We will enroll a well-characterized cohort of persons with COPD and will comprehensively assess physiological and psychosocial outcomes. Results of this study will provide the evidence base for persons with COPD to engage in Tai Chi as a low-cost, long-term modality to sustain physical activity in persons who have completed a standard short-term pulmonary rehabilitation program.

trial registrationThis trial is registered in Clinical Trials.gov, with the ID number of NCT01998724.

Indexed as

Quality of LifeAdultAffectAgedDyspneaFemaleHumansMaleMiddle AgedPatient CompliancePhysical FitnessPulmonary Disease, Chronic ObstructiveResearch DesignSelf EfficacyTai JiChronic obstructive pulmonary diseaseExerciseMind–body therapiesPhysical activityPulmonary rehabilitation

Identifiers

PMID26362690
PMCPMC4886504
OpenAlexW1855450594

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.