Evidence map›Paper›PMID 26362635›Full record

ArticleCirculation2015

Arrhythmia Protection in Hypokalemia: A Novel Role of Ca2+-Activated K+ Currents in the Ventricle.

Michela Faggioni, Björn C Knollmann

Abstract readEditorialComment
In one paragraph

Article in Circulation, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Atrial arrhythmogenesis and electrophysiological remodeling in hypokalaemic metabolic syndrome: the role of apamin-sensitive SK channels.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Article
  3. NaInternational journal of cardiology. Heart & vasculature · 2025
    Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Michela FaggioniFrom Division of Cardiovascular Medicine, Cardio-Thoracic and Vascular Department, University of Pisa, Italy (M.F.); and Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University, Nashville, TN (B.C.K.).
Björn C KnollmannFrom Division of Cardiovascular Medicine, Cardio-Thoracic and Vascular Department, University of Pisa, Italy (M.F.); and Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University, Nashville, TN (B.C.K.). bjorn.knollmann@vanderbilt.edu.

Funding

Troponin T mutations and Sudden Cardiac DeathR01HL071670 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI KNOLLMANN, BJORN C · 2003 to 2017
$4.5M
Calsequestrin in Ventricular Arrhythmia and Sudden DeathR01HL088635 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI KNOLLMANN, BJORN C · 2007 to 2015
$3.2M
Toward a Mechanism-Based Approach to Treating Atrial FibrillationR01HL124935 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI KNOLLMANN, BJORN C · 2015 to 2019
$2.8M
NHLBI NIH HHS R01 HL071670NHLBI NIH HHS R01 HL088635NHLBI NIH HHS R01 HL124935
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cardiac Pacing, ArtificialAnimalsHeart Conduction SystemHypokalemiaIntermediate-Conductance Calcium-Activated Potassium ChannelsPotassiumVentricular FibrillationIntermediate-Conductance Calcium-Activated Potassium ChannelsPotassiumcalciumEditorialshypokalemia

Identifiers

PMID26362635
PMCPMC4605887

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.