ArticleLangenbeck's archives of surgery2015
Algorithm for early discharge after total thyroidectomy using PTH to predict hypocalcemia: prospective study.
Article in Langenbeck's archives of surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Definition and diagnosis of postsurgical hypoparathyroidism after thyroid surgery: meta-analysis.BJS open · 2022Pooled it
- Early prediction of hypocalcemia following thyroid surgery. A prospective randomized clinical trial.Langenbeck's archives of surgery · 2017Trial
- Incidental Parathyroidectomy After Thyroid Surgery: A Single-Center Study.Biomedicines · 2024Article
- A symptom-based algorithm for calcium management after thyroid surgery: a prospective multicenter study.European thyroid journal · 2023Article
- Risk Factors for Hypoparathyroidism after Thyroid Surgery: A Single-Center Study.Journal of clinical medicine · 2023Article
- Parathyroid Hormone Reduction Predicts Transient Hypocalcemia after Total Thyroidectomy: A Single-Center Prospective Study.International journal of endocrinology · 2020Article
- Incidence, prevalence and risk factors for post-surgical hypocalcaemia and hypoparathyroidism.Gland surgery · 2017Review
- Prolonged Duration of Surgery Predicts Postoperative Hypoparathyroidism among Patients Undergoing Total Thyroidectomy in a Tertiary Referral Centre.European thyroid journal · 2017Article
- Hypomagnesemia predicts postoperative biochemical hypocalcemia after thyroidectomy.BMC surgery · 2017Article
- Protocol for management after thyroidectomy: a retrospective study based on one-center experience.Therapeutics and clinical risk management · 2017Article
- EARLIER PREDICTION OF HYPOCALCEMIA BY POSTOPERATIVE SECOND HOUR PARATHYROID HORMONE LEVEL AFTER TOTAL THYROIDECTOMY.Acta endocrinologica (Bucharest, Romania : 2005)Article
- Early discharge after total thyroidectomy: a retrospective feasibility study.Il Giornale di chirurgiaArticle
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeHypocalcemia is the most common complication after total thyroidectomy. The aim of this study was to determine whether postoperative parathyroid hormone (PTH) levels predict hypocalcemia in order to design an algorithm for early discharge.
methodsWe present a prospective study including patients who underwent total thyroidectomy. Hypocalcemia was defined as serum ionized calcium < 1.09 mmol/L or clinical evidence of hypocalcemia. PTH measurement was performed preoperatively and at 1, 3, and 6 h postoperatively. The percent decline of preoperative values was calculated for each time point.
resultsOne hundred and six patients were included. Thirty-six (33.9%) patients presented hypocalcemia. A 50% decline in PTH levels at 3 h postoperatively showed the highest sensitivity and specificity to predict hypocalcemia (91 and 73%, respectively). No patients with a decrease <35% developed hypocalcemia (100% sensitivity), and all patients with a decrease >80% had hypocalcemia (100% specificity).
conclusionsPTH determination at 3 h postoperatively is a reliable predictor of hypocalcemia. According to the proposed algorithm, patients with less than 80% drop in PTH levels can be safely discharged the day of the surgery.
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