Trial reportJournal of geriatric oncology2015
Symptoms, weight loss, and physical function in a lifestyle intervention study of older cancer survivors.
Trial report in Journal of geriatric oncology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Effect of Home- and Community-Based Physical Activity Interventions on Physical Function Among Cancer Survivors: A Systematic Review and Meta-Analysis.Archives of physical medicine and rehabilitation · 2017Pooled it
- Feasibility and potential efficacy of commercial mHealth/eHealth tools for weight loss in African American breast cancer survivors: pilot randomized controlled trial.Translational behavioral medicine · 2020Trial
- Effects of a physical activity programme to prevent physical performance decline in onco-geriatric patients: a randomized multicentre trial.Journal of cachexia, sarcopenia and muscle · 2019Trial
- SurvivorCHESS to increase physical activity in colon cancer survivors: can we get them moving?Journal of cancer survivorship : research and practice · 2018Trial
- Quality of life outcomes from the Exercise and Nutrition Enhance Recovery and Good Health for You (ENERGY)-randomized weight loss trial among breast cancer survivors.Breast cancer research and treatment · 2015Trial
- Adherence to Survivorship Care Visits in Patients With Cervical Cancer in Botswana.JCO global oncology · 2026Observational
- Preliminary Effectiveness of a Telehealth-Delivered Exercise Program in Older Adults Living With and Beyond Cancer: Retrospective Study.JMIR cancer · 2025Article
- Survival Outcomes for Men over 80 Years Undergoing Transrectal Ultrasound-Guided Prostate Biopsy: A Prospective Analysis.Cancers · 2024Article
- A scoping review of diet and exercise interventions for older cancer survivors' physical function.Journal of geriatric oncology · 2024Article
- E-PROOF: E-intervention for protein intake and resistance training to optimize function: A study protocol.PloS one · 2024Article
- U-shaped association between body mass index and health-related quality of life impairment in Korean cancer survivors: a nationwide representative cross-sectional survey.Journal of cancer survivorship : research and practice · 2023Article
- Predictors of the 6-min walk test in patients with ovarian cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Article
- Metabolic Classification and Intervention Opportunities for Tumor Energy Dysfunction.Metabolites · 2021Review
- Treatment and patient related quality of life issues in elderly and very elderly breast cancer patients.Translational cancer research · 2020Review
- Association between hand grip strength and impaired health-related quality of life in Korean cancer survivors: a cross-sectional study.BMJ open · 2019Article
- Association Between Symptom Burden and Physical Function in Older Patients with Cancer.Journal of the American Geriatrics Society · 2019Article
- Healthcare experience among older cancer survivors: Analysis of the SEER-CAHPS dataset.Journal of geriatric oncology · 2018Article
- Stage Validity of the Health Action Process Approach in African American Breast Cancer Survivors.Journal of immigrant and minority health · 2018Article
- Outcomes of patients older than 75 years with non-metastatic prostate cancer.Asian journal of urology · 2017Article
- Cancer and treatment-related symptoms are associated with mobility disability in women with ovarian cancer: A cross-sectional study.Gynecologic oncology · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 1 country.
Funding
Abstract
objectivesMany older cancer survivors are overweight or obese, with additional illness burden increasing functional decline, which may affect their ability to engage in lifestyle interventions. This study examined how overweight long-term survivors' symptom severity associated with comorbidity prior to a diet and exercise intervention was associated with post-intervention function and examined symptoms' effects on function through change in physical activity, diet quality, and weight status. MATERIALS AND
methodsThis is a secondary data analysis of 514 breast, prostate, and colorectal cancer survivors who participated in the one-year home-based diet and exercise intervention Reach-Out to Enhance Wellness trial. Measures included symptoms, weight, physical activity, diet quality, overall physical function (PF), and basic and advanced lower extremity function (BLEF and ALEF). Simple and serial mediation analyses were conducted to examine direct effects of symptom severity on PF, BLEF, and ALEF and indirect effects of symptom severity through changes in diet quality, physical activity, and weight.
resultsSymptom severity was directly associated with lower functioning scores for PF (b=-0.63 p<0.001), BLEF (b=-0.33, p<0.001), and ALEF (b=-0.22, p<0.001). Indirect effects of symptom severity through weight loss, physical activity, and diet were not significant. Weight loss and physical activity were associated with higher PF and ALEF and diet quality was associated with higher BLEF.
conclusionSymptom severity of older, overweight cancer survivors negatively affects physical function. However, greater weight loss and more physical activity were associated with higher functioning scores, regardless of symptom severity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.