Evidence map›Paper›PMID 26362345›Full record

ArticleJournal of biomedical informatics2015

Exploiting the UMLS Metathesaurus for extracting and categorizing concepts representing signs and symptoms to anatomically related organ systems.

Le-Thuy T Tran, Guy Divita, Marjorie E Carter, Joshua Judd, Matthew H Samore, Adi V Gundlapalli

Open access · greenAbstract read
In one paragraph

Article in Journal of biomedical informatics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Clinical Concept Extraction with Lexical Semantics to Support Automatic Annotation.International journal of environmental research and public health · 2021
    Article
  3. Review
  4. Assessing the enrichment of dietary supplement coverage in the Unified Medical Language System.Journal of the American Medical Informatics Association : JAMIA · 2020
    Article
  5. Using UMLS for electronic health data standardization and database design.Journal of the American Medical Informatics Association : JAMIA · 2020
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Le-Thuy T TranIDEAS Center, VA Salt Lake City Health Care System, Salt Lake City, UT, United States; Department of Biomedical Informatics, University of Utah School of Medicine, Salt Lake City, UT, United States.
Guy DivitaIDEAS Center, VA Salt Lake City Health Care System, Salt Lake City, UT, United States; Department of Biomedical Informatics, University of Utah School of Medicine, Salt Lake City, UT, United States.
Marjorie E CarterIDEAS Center, VA Salt Lake City Health Care System, Salt Lake City, UT, United States.
Joshua JuddIDEAS Center, VA Salt Lake City Health Care System, Salt Lake City, UT, United States.
Matthew H SamoreIDEAS Center, VA Salt Lake City Health Care System, Salt Lake City, UT, United States; Department of Biomedical Informatics, University of Utah School of Medicine, Salt Lake City, UT, United States; Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT, United States.
Adi V GundlapalliIDEAS Center, VA Salt Lake City Health Care System, Salt Lake City, UT, United States; Department of Biomedical Informatics, University of Utah School of Medicine, Salt Lake City, UT, United States; Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT, United States. Electronic address: adi.gundlapalli@hsc.utah.edu.
University of Utah · USVA Salt Lake City Healthcare System · US

Funding

UNIVERSITY OF UTAH MEDICAL INFORMATICS TRAININGT15LM007124 · NLM · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Karen Louise Eilbeck · 1997 to 2026
$22.0M
HSRD VA HIR 10-001NLM NIH HHS T15 LM007124NLM NIH HHS T15LM007124
6 · The paper itself

Abstract

objectiveTo develop a method to exploit the UMLS Metathesaurus for extracting and categorizing concepts found in clinical text representing signs and symptoms to anatomically related organ systems. The overarching goal is to classify patient reported symptoms to organ systems for population health and epidemiological analyses. MATERIALS AND

methodsUsing the concepts' semantic types and the inter-concept relationships as guidance, a selective portion of the concepts within the UMLS Metathesaurus was traversed starting from the concepts representing the highest level organ systems. The traversed concepts were chosen, filtered, and reviewed to obtain the concepts representing clinical signs and symptoms by blocking deviations, pruning superfluous concepts, and manual review. The mapping process was applied to signs and symptoms annotated in a corpus of 750 clinical notes.

resultsThe mapping process yielded a total of 91,000 UMLS concepts (with approximately 300,000 descriptions) possibly representing physical and mental signs and symptoms that were extracted and categorized to the anatomically related organ systems. Of 1864 distinct descriptions of signs and symptoms found in the 750 document corpus, 1635 of these (88%) were successfully mapped to the set of concepts extracted from the UMLS. Of 668 unique concepts mapped, 603 (90%) were correctly categorized to their organ systems.

conclusionWe present a process that facilitates mapping of signs and symptoms to their organ systems. By providing a smaller set of UMLS concepts to use for comparing and matching patient records, this method has the potential to increase efficiency of information extraction pipelines.

Indexed as

AnatomyConcept FormationUnified Medical Language SystemHumansInformation extractionSemantic mappingSymptomsUMLS Metathesaurus

Identifiers

PMID26362345
PMCPMC4871278
OpenAlexW2106972184

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.