ReviewProtein science : a publication of the Protein Society2015
Structural and mechanistic insights on nitrate reductases.
Review in Protein science : a publication of the Protein Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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32 citing papers in PubMed, 88 citations in OpenAlex.
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- Structure and function of periplasmic nitrate reductase.Biochemical Society transactions · 2026Review
- Cross-scale understanding of cascade electrocatalysis for carbon and nitrogen utilization.Chemical science · 2026Review
- Foliar application of magnesium and amino acids to off-season maize: a strategy to improve photosynthetic and antioxidant metabolism.Frontiers in plant science · 2026Article
- Structure and substrate promiscuity of Campylobacter jejuni periplasmic nitrate reductase (Nap) and phylogenetic analysis of Nap homologs.The Journal of biological chemistry · 2025Article
- Characterization and Evolutionary Study of Fungal Nitrate Reductase Through Bioinformatics and Partial Gene Amplification from Aspergillus niger PKA16 employing Degenerate Primers.The protein journal · 2025Article
- Electronic Modification of a Reduced Mononuclear Nonheme Iron Nitrosyl Complex Leads to HNO Release.Journal of the American Chemical Society · 2025Article
- Biogenic Synthesis of Silver Nanoparticles and Their Diverse Biomedical Applications.Molecules (Basel, Switzerland) · 2025Review
- Nitrate-Nitrite Interplay in the Nitrogen Biocycle.Molecules (Basel, Switzerland) · 2025Review
- A new heme enzyme family forms hydrazine groups in diverse biosynthetic pathways.bioRxiv : the preprint server for biology · 2025Article
- Magnesium application partially reversed the negative effects of mulching on rhizosphere nitrogen cycling in aFrontiers in plant science · 2025Article
- Insights into periplasmic nitrate reductase function under single turnover.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2024Article
- Stable isotopic signature of dissimilatory nitrate reduction is robust against enzyme mutation.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Assessing the effects of NapA gene overexpression on denitrification and denitrogenation in magnetospirillum gryphiswaldense MSR-1.Archives of microbiology · 2024Article
- A positive contribution to nitrogen removal by a novel NOB in a full-scale duck wastewater treatment system.Water research X · 2024Article
- Unraveling nitrogen metabolism, cold and stress adaptation in polarFrontiers in microbiology · 2024Article
- A gene network-driven approach to infer novel pathogenicity-associated genes: application tomSystems · 2023Article
- Microorganisms for the oxidation of nitrated cellulose in its effluents (review).Biophysical reviews · 2023Review
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nitrate reductases (NR) belong to the DMSO reductase family of Mo-containing enzymes and perform key roles in the metabolism of the nitrogen cycle, reducing nitrate to nitrite. Due to variable cell location, structure and function, they have been divided into periplasmic (Nap), cytoplasmic, and membrane-bound (Nar) nitrate reductases. The first crystal structure obtained for a NR was that of the monomeric NapA from Desulfovibrio desulfuricans in 1999. Since then several new crystal structures were solved providing novel insights that led to the revision of the commonly accepted reaction mechanism for periplasmic nitrate reductases. The two crystal structures available for the NarGHI protein are from the same organism (Escherichia coli) and the combination with electrochemical and spectroscopic studies also lead to the proposal of a reaction mechanism for this group of enzymes. Here we present an overview on the current advances in structural and functional aspects of bacterial nitrate reductases, focusing on the mechanistic implications drawn from the crystallographic data.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.