ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2015
Association of Influenza Vaccination Coverage in Younger Adults With Influenza-Related Illness in the Elderly.
Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 18 citations in OpenAlex.
- A New Look at Vaccination Behaviors and Intentions: The Case of Influenza.Behavioral sciences (Basel, Switzerland) · 2025Article
- Hospitalization and risk of death due to influenza among vaccinated and unvaccinated patients. A 5-year study in the northeastern Mexican population.Human vaccines & immunotherapeutics · 2022Article
- The impact of personal coaching on influenza vaccination among healthcare workers before and during COVID-19 pandemic.Vaccine · 2022Article
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- The Clinical Effect of Seasonal Flu Vaccination on Health-Related Quality of Life.International journal of general medicine · 2021Article
- Influenza Vaccination and COVID19 Mortality in the USA.medRxiv : the preprint server for health sciences · 2020Article
- Respiratory Virus Infections in People Over 14 Years of Age in Poland in the Epidemic Season of 2017/18.Advances in experimental medicine and biology · 2019Article
- The Hurdles From Bench to Bedside in the Realization and Implementation of a Universal Influenza Vaccine.Frontiers in immunology · 2018Review
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundOlder adults have the highest influenza-related morbidity and mortality risk, but the influenza vaccine is less effective in the elderly. It is unknown whether influenza vaccination of nonelderly adults confers additional disease protection on the elderly population.
methodsWe examined the association between county-wide influenza vaccination coverage among 520 229 younger adults (aged 18-64 years) in the Behavioral Risk Factors Surveillance System Survey and illnesses related to influenza in 3 317 709 elderly Medicare beneficiaries aged ≥65 years, between 2002 and 2010 (13 267 786 person-years). Results were stratified by documented receipt of a seasonal influenza vaccine in each Medicare beneficiary.
resultsIncreases in county-wide vaccine coverage among younger adults were associated with lower adjusted odds of illnesses related to influenza in the elderly. Compared with elderly residents of counties with ≤15% of younger adults vaccinated, the adjusted odds ratio for a principal diagnosis of influenza among elderly residents was 0.91 (95% confidence interval, .88-.94) for counties with 16%-20% of younger adults vaccinated, 0.87 (.84-.90) for counties with 21%-25% vaccinated, 0.80 (.77-.83) for counties with 26%-30% vaccinated, and 0.79 (.76-.83) for counties with ≥31% vaccinated (P for trend <.001). Stronger associations were observed among vaccinated elderly adults, in peak months of influenza season, in more severe influenza seasons, in influenza seasons with greater antigenic match to influenza vaccine, and for more specific definitions of influenza-related illness.
conclusionsIn a large, nationwide sample of Medicare beneficiaries, influenza vaccination among adults aged 18-64 years was inversely associated with illnesses related to influenza in the elderly.
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