ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2016
The associations of physical activity with fracture risk--a 7-year prospective controlled intervention study in 3534 children.
Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
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Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- The Benefits to Bone Health in Children and Pre-School Children with Additional Exercise Interventions: A Systematic Review and Meta-Analysis.Nutrients · 2022Pooled it
- School-based physical activity programs for promoting physical activity and fitness in children and adolescents aged 6 to 18.The Cochrane database of systematic reviews · 2021Pooled it
- Fracture Incidence With 6-9 Years of Daily School Physical Activity: Lower Relative Fracture Risk at the End of the Intervention But Not After.Scandinavian journal of medicine & science in sports · 2026Article
- Racial/Ethnic Differences in Bone Mineral Density for Osteoporosis.Current osteoporosis reports · 2023Review
- Exposure to Neighborhood Walkability and Residential Greenness and Incident Fracture.JAMA network open · 2023Article
- Bone Health in Young Athletes: a Narrative Review of the Recent Literature.Current osteoporosis reports · 2023Review
- Decreases in pediatric fractures during the COVID-19 pandemic - a nationwide epidemiological cohort study.European journal of pediatrics · 2022Article
- Physical Activity in Late Prepuberty and Early Puberty Is Associated With High Bone Formation and Low Bone Resorption.Frontiers in physiology · 2022Article
- Musculoskeletal Benefits from a Physical Activity Program in Primary School are Retained 4 Years after the Program is Terminated.Calcified tissue international · 2021Article
- Time trends in pediatric hand fracture incidence in Malmö, Sweden, 1950-2016.Journal of orthopaedic surgery and research · 2021Article
- Childhood Distal Forearm Fracture Incidence in Malmö, Sweden 1950 to 2016.Journal of wrist surgery · 2021Article
- Weight Management in Youth with Type 1 Diabetes and Obesity: Challenges and Possible Solutions.Current obesity reports · 2020Review
- Exercise and Peak Bone Mass.Current osteoporosis reports · 2020Review
- Daily School Physical Activity from Before to After Puberty Improves Bone Mass and a Musculoskeletal Composite Risk Score for Fracture.Sports (Basel, Switzerland) · 2020Article
- Pediatric Distal Forearm Fracture Epidemiology in Malmö, Sweden-Time Trends During Six Decades.Journal of wrist surgery · 2019Article
- Do teenagers return to normal physical activity levels after limb fractures? A longitudinal, accelerometry-based, activity monitoring study.Journal of children's orthopaedics · 2019Article
- Hand fracture epidemiology and etiology in children-time trends in Malmö, Sweden, during six decades.Journal of orthopaedic surgery and research · 2019Article
- Low physical activity is related to clustering of risk factors for fracture-a 2-year prospective study in children.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017Article
- Do bone mineral content and density determine fracture in children? A possible threshold for physical activity.Pediatric research · 2017Article
- Time trends in pediatric fracture incidence in Sweden during the period 1950-2006.Acta orthopaedica · 2017Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
summaryThis is the first study indicating an association between gradually diminished risk of fractures and years of increased physical activity. Our results could imply great benefits not only for the individual but also for the healthcare burden and cost of society.
introductionPhysical activity (PA) in childhood is associated with high bone mass and beneficial neuromuscular function. We investigate if increased PA also is associated with fracture risk.
methodsWe registered fractures in 3534 children aged 6 to 8 years at study start for up to 7 years; 1339 with 40 min of moderate PA every school day (intervention) and 2195 with the Swedish standard curriculum of 60 min of PA per school week (controls). In a subsample of 264 children, we measured areal bone mineral density (aBMD; g/cm(2)) with dual-energy X-ray absorptiometry (femoral neck and total spine) and muscle strength (peak torque for knee extension and flexion; Nm) with computerized dynamometer at baseline and after 7 years. We estimated annual fracture incidence rate ratios (IRR) in the intervention group compared to the control group as well as changes in bone mass and muscle strength. Data is given as mean (95% CI).
resultsThe IRR of fractures decreased with each year of the PA intervention (r = -0.79; p = 0.04). During the seventh year, IRR was almost halved [IRR 0.52 (0.27, 1.01)]. The intervention group had a statistically significant greater gain in total spine aBMD with a mean group difference of 0.03 (0.00, 0.05) g/cm(2) and peak flexion torque 180° with a mean group difference of 5.0 (1.5, 8.6) Nm.
conclusionsIncreased PA is associated with decreased fracture risk, probably in part due to beneficial gains in aBMD and muscle strength.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.