ArticleScientific reports2015
Different expression domains for two closely related amphibian TAARs generate a bimodal distribution similar to neuronal responses to amine odors.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Vertebrate-wide transcriptomic screening identifies immune cell-specific expression of the conserved OR-κ gene.Zoological letters · 2026Article
- Spatial organization of olfactory receptor gene choice in the complete V1R-related ORA family of zebrafish.Scientific reports · 2022Article
- Evaluation of Approach to a Conspecific and Blood Biochemical Parameters in TAAR1 Knockout Mice.Brain sciences · 2022Article
- Olfactory subsystems in the peripheral olfactory organ of anuran amphibians.Cell and tissue research · 2021Review
- Olfactory signaling via trace amine-associated receptors.Cell and tissue research · 2021Review
- Differential expression of olfactory genes in Atlantic salmon (Ecology and evolution · 2019Article
- Trace Amine-Associated Receptors as Novel Therapeutic Targets for Immunomodulatory Disorders.Frontiers in pharmacology · 2018Article
- The Evolving Neural and Genetic Architecture of Vertebrate Olfaction.Current biology : CB · 2016Review
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6 authors.
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Abstract
Olfactory perception is mediated by a multitude of olfactory receptors, whose expression in the sensory surface, the olfactory epithelium, is spatially regulated. A common theme is the segregation of different olfactory receptors in different expression domains, which in turn leads to corresponding segregation in the neuronal responses to different odor groups. The amphibian olfactory receptor gene family of trace amine associated receptors, in short TAARs, is exceedingly small and allows a comprehensive analysis of spatial expression patterns, as well as a comparison with neuronal responses to the expected ligands for this receptor family, amines. Here we report that TAAR4b exhibits a spatial expression pattern characteristically different in two dimensions from that of TAAR4a, its close homolog. Together, these two genes result in a bimodal distribution resembling that of amine responses as visualized by calcium imaging. A stringent quantitative analysis suggests the involvement of additional olfactory receptors in amphibian responses to amine odors.
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