Evidence map›Paper›PMID 26358536›Full record

Trial reportContemporary clinical trials2015

Design of the FRESH study: A randomized controlled trial of a parent-only and parent-child family-based treatment for childhood obesity.

Kerri N Boutelle, Abby Braden, Jennifer M Douglas, Kyung E Rhee, David Strong, Cheryl L Rock, Denise E Wilfley, Leonard Epstein, Scott Crow

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Contemporary clinical trials, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03326128 (High Dose Bupropion Treatment for Smoking Cessation - Pilot Study), which is not on this map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03326128 phase2terminatednot on this mapstarted 2021, after this paper: background citation

High Dose Bupropion Treatment for Smoking Cessation - Pilot Study

TypeinterventionalSponsorUniversity of Southern CaliforniaRan2021 to 2023Enrolled12ConditionsSmoking Cessation, Smoking, Tobacco, Smoking (Tobacco) Addiction, Cessation, TobaccoArmsBupropion Hydrochloride
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. A developmental cascade perspective of paediatric obesity: A systematic review of preventive interventions from infancy through late adolescence.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2020
    Pooled it
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  10. Family-based treatment program contributors to child weight loss.International journal of obesity (2005) · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kerri N BoutelleUniversity of California San Diego, Department of Pediatrics, United States; University of California San Diego, Department of Psychiatry, United States. Electronic address: kboutelle@ucsd.edu.
Abby BradenUniversity of California San Diego, Department of Pediatrics, United States.
Jennifer M DouglasUniversity of California San Diego, Department of Pediatrics, United States.
Kyung E RheeUniversity of California San Diego, Department of Pediatrics, United States.
David StrongUniversity of California, San Diego, Department of Family Medicine and Public Health, United States.
Cheryl L RockUniversity of California, San Diego, Department of Family Medicine and Public Health, United States.
Denise E WilfleyWashington University in St. Louis School of Medicine, Department of Psychiatry, United States.
Leonard EpsteinUniversity at Buffalo, Department of Pediatrics, United States.
Scott CrowUniversity of Minnesota, Department of Psychiatry, United States; The Emily Program, United States.

Funding

Obesity and Energy Metabolism CoreP30DK050456 · NIDDK · UNIVERSITY OF MINNESOTA TWIN CITIES · PI BERNLOHR, DAVID A · 1995 to 2015
$17.0M
Parents as the Agent of Change for Childhood ObesityR01DK075861 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BOUTELLE, KERRI N · 2010 to 2014
$3.0M
The treatment of childhood obesityK02HL112042 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BOUTELLE, KERRI N · 2012 to 2014
$321k
NHLBI NIH HHS K02 HL112042NIDDK NIH HHS P30 DK050456NIDDK NIH HHS P30 DK50456NIDDK NIH HHS R01 DK075861
6 · The paper itself

Abstract

Approximately 1 out of 3 children in the United States is overweight or obese. Family-based treatment (FBT) is considered the gold-standard treatment for childhood obesity, but FBT is both staff and cost intensive. Therefore, we developed the FRESH (Family, Responsibility, Education, Support, & Health) study to evaluate the effectiveness of intervening with parents, without child involvement, to facilitate and improve the child's weight status. Targeting parents directly in the treatment of childhood obesity could be a promising approach that is developmentally appropriate for grade-school age children, highly scalable, and may be more cost effective to administer. The current paper describes the FRESH study which was designed to compare the effectiveness of parent-based therapy for pediatric obesity (PBT) to a parent and child (FBT) program for childhood obesity. We assessed weight, diet, physical activity, and parenting, as well as cost-effectiveness, at baseline, post-treatment, and at 6- and 18-month follow-ups. Currently, all participants have been recruited and completed assessment visits, and the initial stages of data analysis are underway. Ultimately, by evaluating a PBT model, we hope to optimize available child obesity treatments and improve their translation into clinical settings.

Indexed as

Body Mass IndexChildDietExerciseFemaleHealth BehaviorHealth EducationHealth PromotionHumansMaleOverweightParent-Child RelationsParentsPediatric ObesityResearch DesignSocioeconomic FactorsChildFamily-based treatmentObesityRandomized controlled trial

Identifiers

PMID26358536
PMCPMC4683105

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.