ArticlePediatric nephrology (Berlin, Germany)2016
Urinary tract infection in infants: the significance of low bacterial count.
Article in Pediatric nephrology (Berlin, Germany), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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19 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.
- Evidence-based clinical practice guideline for management of urinary tract infection and primary vesicoureteric reflux.Pediatric nephrology (Berlin, Germany) · 2024Guideline
- Urinalysis Accuracy for Diagnosis of Bacteremic Urinary Tract Infections in 0-3-Month-Old Infants.Acta paediatrica (Oslo, Norway : 1992) · 2025Article
- Infant urinary tract infection in Sweden - A national study of current diagnostic procedures, imaging and treatment.Pediatric nephrology (Berlin, Germany) · 2024Article
- Urinary tract infection guidelines should address unique, specific questions and include analyses of primary data.Pediatric nephrology (Berlin, Germany) · 2024Article
- Association Between Antibiotic Duration and Recurrence of Urinary Tract Infection in the Neonatal Critical Care Unit.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2024Article
- Urinary tract infections in very premature neonates: the definition dilemma.Journal of perinatology : official journal of the California Perinatal Association · 2024Article
- Support for the Use of a New Cutoff to Define a Positive Urine Culture in Young Children.Pediatrics · 2023Article
- Epidemiology, risk factors, and applicability of CDC definitions for healthcare-associated bloodstream infections at a level IV neonatal ICU.Journal of perinatology : official journal of the California Perinatal Association · 2023Article
- Clinical guidelines of UTIs in children: quality appraisal with AGREE II and recommendations analysis.BMJ open · 2022Article
- How Swedish guidelines on urinary tract infections in children compare to Canadian, American and European guidelines.Acta paediatrica (Oslo, Norway : 1992) · 2021Article
- Current Management of Urinary Tract Infection and Vesicoureteral Reflux.Indian journal of pediatrics · 2020Review
- Urinary tract infections in children.Lancet (London, England) · 2020Review
- Defining urinary tract infection by bacterial colony counts: a case for 100,000 colonies/ml as the best threshold.Pediatric nephrology (Berlin, Germany) · 2019Article
- Update on Associated Risk Factors, Diagnosis, and Management of Recurrent Urinary Tract Infections in Children.Journal of the Pediatric Infectious Diseases Society · 2019Review
- Urinary Tract Infection in Children.Recent patents on inflammation & allergy drug discovery · 2019Article
- What Urinary Colony Count Indicates a Urinary Tract Infection in Children?The Journal of pediatrics · 2017Article
- Urine neutrophil gelatinase-associated lipocalin and other biomarkers in infants with urinary tract infection and in febrile controls.Pediatric nephrology (Berlin, Germany) · 2017Article
- Diagnosis of Urinary Tract Infections in Children.Journal of clinical microbiology · 2016Review
- Low urinary bacterial counts: do they count?Pediatric nephrology (Berlin, Germany) · 2016Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn national guidelines for urinary tract infection (UTI) in children, different cut-off levels for defining bacteriuria are used. In this study, the relationship between bacterial count in infant UTI and inflammatory parameters, frequency of vesicoureteral reflux (VUR), kidney damage, and recurrent UTI was analyzed.
methodsWe conducted a population-based retrospective study of 430 infants age <1 year with symptomatic UTI diagnosed by suprapubic aspiration. Clinical and laboratory parameters, findings on voiding cystourethrography and (99m)technetium dimercapto-succinic acid scintigraphy, and frequency of recurrence were related to bacterial count at the index UTI.
resultsEighty-three (19%) infants had bacterial counts <100,000 colony-forming units (CFU)/ml and 347 (81%) had ≥100,000 CFU/ml. There was similar frequency of VUR (19% in both groups), kidney damage (17 and 23%, p = 0.33) and recurrent UTI (6 and 12%, p = 0.17) in the low and high bacterial group. Non-E. coli species were more prevalent (19 versus 6%, p = 0.0006) and mean C-reactive protein was lower (50 vs. 79 mg/l, p <0.0001) in the low bacteria group.
conclusionsUTI with low bacterial count is common and of importance since it may be associated with VUR and renal damage. Non-E. coli species and low inflammatory response were more prevalent in UTI with low bacterial count.
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