Evidence map›Paper›PMID 26358180›Full record

ArticleBiomacromolecules2015

Preparation of Dental Resins Resistant to Enzymatic and Hydrolytic Degradation in Oral Environments.

Andres Gonzalez-Bonet, Gili Kaufman, Yin Yang, Christopher Wong, Abigail Jackson, George Huyang, Rafael Bowen, Jirun Sun

Open access · greenAbstract read
In one paragraph

Article in Biomacromolecules, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 87 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Evaluation of Polymerization Shrinkage, Microhardness, and Depth of Cure of Different Types of Bulk-Fill Composites.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2025
    Article
  6. Evolution of Dental Resin Adhesives-A Comprehensive Review.Journal of functional biomaterials · 2025
    Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Novel antibacterial low-shrinkage-stress resin-based cement.Dental materials : official publication of the Academy of Dental Materials · 2022
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Andres Gonzalez-BonetDr. Anthony Volpe Research Center, American Dental Association Foundation, National Institute of Standards and Technology , Gaithersburg, Maryland 20899, United States.
Gili KaufmanDr. Anthony Volpe Research Center, American Dental Association Foundation, National Institute of Standards and Technology , Gaithersburg, Maryland 20899, United States.
Yin YangDr. Anthony Volpe Research Center, American Dental Association Foundation, National Institute of Standards and Technology , Gaithersburg, Maryland 20899, United States.
Christopher WongDr. Anthony Volpe Research Center, American Dental Association Foundation, National Institute of Standards and Technology , Gaithersburg, Maryland 20899, United States.
Abigail JacksonDr. Anthony Volpe Research Center, American Dental Association Foundation, National Institute of Standards and Technology , Gaithersburg, Maryland 20899, United States.
George HuyangDr. Anthony Volpe Research Center, American Dental Association Foundation, National Institute of Standards and Technology , Gaithersburg, Maryland 20899, United States.
Rafael BowenDr. Anthony Volpe Research Center, American Dental Association Foundation, National Institute of Standards and Technology , Gaithersburg, Maryland 20899, United States.
Jirun SunDr. Anthony Volpe Research Center, American Dental Association Foundation, National Institute of Standards and Technology , Gaithersburg, Maryland 20899, United States.
National Institute of Standards and Technology · USAmerican Dental Association · US

Funding

Novel Dental Resin Composites with Improved Service LifeU01DE023752 · NIDCR · AMERICAN DENTAL ASSOCIATION FOUNDATION · PI SUN, JIRUN · 2013 to 2017
$2.2M
Effects of Biofilm Activities and Dental Resin Composite Compositions on the DeveR01DE021391 · NIDCR · UNIVERSITY OF COLORADO DENVER · PI CAREY, CLIFTON M · 2010 to 2013
$1.4M
NIDCR NIH HHS R01 DE021391NIDCR NIH HHS U01 DE023752NIDCR NIH HHS U01DE023752
6 · The paper itself

Abstract

The short average service life of traditional dental composite restorative materials and increasing occurrence of secondary caries adjacent to composite restorations and sealants are necessitating the development of new, longer lasting compositions. Novel monomers and their polymers, reinforcing fillers, and adhesive components are needed. The goal of this research is to develop resin systems for use in restorations, sealants, and other dental services that are superior in properties and endurance to currently used bisphenol A glycidyl dimethacrylate/triethylene glycol dimethacrylate (Bis-GMA/TEGDMA) and urethane-dimethacrylate products. Ether-based monomers and their polymers that were not susceptible to enzymatic or hydrolytic degradation were prepared and characterized. They showed no degradation under hydrolytic and enzymatic challenges, whereas the hydrolysis of ester links weakened contemporary resins within 16 days under these challenges. The success of the ether-based materials is promising in making durable systems that are subjected to long-term biochemical and hydrolytic challenges in oral environments.

Indexed as

Composite ResinsChromatography, High Pressure LiquidEnzymesHydrolysisMouthSpectroscopy, Fourier Transform InfraredComposite ResinsEnzymes

Identifiers

PMID26358180
PMCPMC4788384
OpenAlexW2271469487

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.