Evidence map›Paper›PMID 26357524›Full record

ReviewEvidence-based complementary and alternative medicine : eCAM2015

Understanding Fibroblasts in Order to Comprehend the Osteopathic Treatment of the Fascia.

Bruno Bordoni, Emiliano Zanier

Registry-linked trialAbstract readReview
In one paragraph

Review in Evidence-based complementary and alternative medicine : eCAM, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05012826 (Osteopathy and Physiotherapy Compared to Physiotherapy Alone on Fatigue and Functional Status in Long COVID), which is not on this map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05012826 naunknown statusnot on this mapstarted 2021, after this paper: background citation

Osteopathy and Physiotherapy Compared to Physiotherapy Alone on Fatigue and Functional Status in Long COVID: Study Protocol for a Pragmatic Randomized Controlled SuperiorityTrial

TypeinterventionalSponsorCentro Universitário Augusto MottaRan2021 to 2023Enrolled104ConditionsCovid19, SARS-CoV-2 InfectionArmsOsteopathic Manipulative Treatment in addition to Physiotherapy, Physiotherapy
3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

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  15. Article
  16. Furnishing Wound Repair by the Subcutaneous Fascia.International journal of molecular sciences · 2021
    Review
  17. Hyaluronan and the Fascial Frontier.International journal of molecular sciences · 2021
    Review
  18. Review
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Bruno BordoniDon Carlo Gnocchi IRCCS, Department of Cardiology, IRCCS S. Maria Nascente Don Carlo Gnocchi Foundation, Via Capecelatro 66, Milano, Italy ; School CRESO, Osteopathic Centre for Research and Studies, Falconara Marittima, Castellanza, Italy ; EdiAcademy, Viale Forlanini 65, Milano, Italy.
Emiliano ZanierSchool CRESO, Osteopathic Centre for Research and Studies, Falconara Marittima, Castellanza, Italy ; EdiAcademy, Viale Forlanini 65, Milano, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The osteopathic treatment of the fascia involves several techniques, each aimed at allowing the various layers of the connective system to slide over each other, improving the responses of the afferents in case of dysfunction. However, before becoming acquainted with a method, one must be aware of the structure and function of the tissue that needs treating, in order to not only better understand the manual approach, but also make a more conscious choice of the therapeutic technique to employ, in order to adjust the treatment to the specific needs of the patient. This paper examines the current literature regarding the function and structure of the fascial system and its foundation, that is, the fibroblasts. These connective cells have many properties, including the ability to contract and to communicate with one another. They play a key role in the transmission of the tension produced by the muscles and in the management of the interstitial fluids. They are a source of nociceptive and proprioceptive information as well, which is useful for proper functioning of the body system. Therefore, the fibroblasts are an invaluable instrument, essential to the understanding of the therapeutic effects of osteopathic treatment. Scientific research should make greater efforts to better understand their functioning and relationships.

Identifiers

PMID26357524
PMCPMC4556860

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.