Evidence map›Paper›PMID 26357472›Full record

ArticleInternational journal of nanomedicine2015

Silica nanoparticle-based dual imaging colloidal hybrids: cancer cell imaging and biodistribution.

Haisung Lee, Dongkyung Sung, Jinhoon Kim, Byung-Tae Kim, Tuntun Wang, Seong Soo A An, Soo-Won Seo, Dong Kee Yi

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 18 citations in OpenAlex.

  1. Synergistic Effect of SiONanomaterials (Basel, Switzerland) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Haisung LeeMolecular Diagnostics, In Vitro Diagnostics Unit, New Business Division, SK Telecom, Republic of Korea.
Dongkyung SungDepartment of Life Sciences, Graduate School of Korea University, Seoul, Republic of Korea.
Jinhoon KimInterdisciplinary Graduate Program of Biomedical Engineering, School of Medicine, Sungkyunkwan University, Samsung Medical Center, Seoul, Republic of Korea.
Byung-Tae KimInterdisciplinary Graduate Program of Biomedical Engineering, School of Medicine, Sungkyunkwan University, Samsung Medical Center, Seoul, Republic of Korea.
Tuntun WangDepartment of Chemistry, Myongji University, Seoul, Republic of Korea.
Seong Soo A AnDepartment of Bionanotechnology, Gachon Medical Research Institute, Gachon University, Seongnam, Republic of Korea.
Soo-Won SeoMedical Device Development Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu, Republic of Korea.
Dong Kee YiDepartment of Chemistry, Myongji University, Seoul, Republic of Korea.
Daegu-Gyeongbuk Medical Innovation Foundation · KRGachon University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, fluorescent dye-conjugated magnetic resonance (MR) imaging agents were investigated in T mode. Gadolinium-conjugated silica nanoparticles were successfully synthesized for both MR imaging and fluorescence diagnostics. Polyamine and polycarboxyl functional groups were modified chemically on the surface of the silica nanoparticles for efficient conjugation of gadolinium ions. The derived gadolinium-conjugated silica nanoparticles were investigated by zeta potential analysis, transmission electron microscopy, inductively coupled plasma mass spectrometry, and energy dispersive x-ray spectroscopy. MR equipment was used to investigate their use as contrast-enhancing agents in T1 mode under a 9.4 T magnetic field. In addition, we tracked the distribution of the gadolinium-conjugated nanoparticles in both lung cancer cells and organs in mice.

Indexed as

Contrast MediaSilicon DioxideAnimalsCell Line, TumorColloidsMagnetic Resonance ImagingMiceNanoparticlesNeoplasmsTissue DistributionColloidsContrast MediaSilicon Dioxidedual bioimagingMR imagingnanohybridsilica colloidT1 contrast imaging

Identifiers

PMID26357472
PMCPMC4559254
OpenAlexW1935766295

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.