Evidence map›Paper›PMID 26356739›Full record

ArticlePuerto Rico health sciences journal2015

Late HIV Testing in a Cohort of HIV-Infected Patients in Puerto Rico.

Katherine Y Tossas-Milligan, Robert F Hunter-Mellado, Angel M Mayor, Diana M Fernández-Santos, Mark S Dworkin

Open access · greenAbstract read
In one paragraph

Article in Puerto Rico health sciences journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Katherine Y Tossas-MilliganDivision of Epidemiology and Biostatistics, University of Illinois at Chicago School of Public Health, 1603 W. Taylor Street, M/C 923, Chicago, IL.
Robert F Hunter-MelladoRetrovirus Research Center, Internal Medicine Department, Universidad Central del Caribe, School of Medicine, Bayamón, PR.
Angel M MayorRetrovirus Research Center, Internal Medicine Department, Universidad Central del Caribe, School of Medicine, Bayamón, PR.
Diana M Fernández-SantosRetrovirus Research Center, Internal Medicine Department, Universidad Central del Caribe, School of Medicine, Bayamón, PR.
Mark S DworkinDivision of Epidemiology and Biostatistics, University of Illinois at Chicago School of Public Health, 1603 W. Taylor Street, M/C 923, Chicago, IL.
Central University of the Caribbean · PRUniversity of Illinois Chicago · US

Funding

TECHNOLOGIES AND RESOURCES FOR CORE LABORATORIESU54MD007587 · NIMHD · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI LUCIANO, CARLOS A., WOJNA, VALERIE · 2012 to 2018
$23.2M
UNIVERSIDAD CENTRAL DEL CARIBE BIOMEDICAL RESEARCH CENTERSG12MD007583 · NIMHD · UNIVERSIDAD CENTRAL DEL CARIBE · PI RODRIGUEZ, JOSE GINEL · 2012 to 2016
$8.4M
NIMHD NIH HHS 8G12MD007583NIMHD NIH HHS 8U54MD007587NIMHD NIH HHS G12 MD007583NIMHD NIH HHS U54 MD007587
6 · The paper itself

Abstract

objectiveLate HIV testing (LT), defined as receiving an AIDS diagnosis within a year of one's first positive HIV test, is associated with higher HIV transmission, lower HAART effectiveness, and worse outcomes. Latinos represent 36% of LT in the US, yet research concerning LT among HIV cases in Puerto Rico is scarce.

methodsMultivariable logistic regression analysis was used to identify factors associated with LT, and a Cochran‒Armitage test was used to determine LT trends in an HIV-infected cohort followed at a clinic in Puerto Rico specialized in the management and treatment of HIV.

resultsFrom 2000 to 2011, 47% of eligible patients were late testers, with lower median CD4 counts (54 vs. 420 cells/mm3) and higher median HIV viral load counts (253,680 vs. 23,700 copies/mL) than non-LT patients. LT prevalence decreased significantly, from 47% in 2000 to 37% in 2011. In a mutually adjusted logistic regression model, males, older age at enrollment and past history of IDU significantly increased LT odds, whereas having a history of amphetamine use decreased LT odds. When the data were stratified by mode of transmission, it became apparent that only the category men who have sex with men (MSM) saw a significant reduction in the proportion of LT, falling from 67% in 2000 to 33% in 2011.

conclusionThese results suggest a gap in early HIV detection in Puerto Rico, a gap that decreased only among MSM. An evaluation of the manner in which current HIV-testing guidelines are implemented on the island is needed.

Indexed as

Acquired Immunodeficiency SyndromeAdolescentAdultAgedAntiretroviral Therapy, Highly ActiveCohort StudiesDelayed DiagnosisFemaleHIV InfectionsHomosexuality, MaleHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisPrevalenceAIDS diagnosisHIV trendsLate HIV diagnosisLate HIV testingPuerto Rico HIV

Identifiers

PMID26356739
PMCPMC4776320
OpenAlexW1741430525

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.