Observational studyMedicine2015
Epidemiology and Medication Utilization Pattern of Aortic Dissection in Taiwan: A Population-Based Study.
Observational study in Medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 48 citations in OpenAlex.
- An Overview of the Diagnostic and Treatment Strategies for Aortic Disease.Reviews in cardiovascular medicine · 2026Review
- Ascending aortic length across a large population presenting to the emergency room, a retrospective cross-sectional study.International journal of cardiology. Heart & vasculature · 2026Article
- Hypertension-Induced Biomechanical Modifications in the Aortic Wall and Their Role in Stanford Type B Aortic Dissection.Biomedicines · 2024Article
- The Prevalence of ST-Segment Elevation Myocardial Infarction in Patients Presenting in the Emergency Service of Galati Hospital from 2015 to 2019.Clinics and practice · 2024Article
- Vascular Endothelial Growth Factor Inhibitors and the Risk of Aortic Aneurysm and Aortic Dissection.JAMA network open · 2024Article
- Current review of acute type A aortic dissection in Malaysia.Indian journal of thoracic and cardiovascular surgery · 2023Review
- Evaluating Prescription Pattern and Effectiveness of Antihypertensive Drugs in Non-Operated Aortic Dissection Patients.Journal of clinical medicine · 2023Article
- Prescription pattern and effectiveness of antihypertensive drugs in patients with aortic dissection who underwent surgery.Frontiers in pharmacology · 2023Article
- Acute aortic dissection (AAD) - a lethal disease: the epidemiology, pathophysiology and natural history.The British journal of cardiology · 2023Article
- Current Surgical Management of Acute Type A Aortic Dissection in China: A Multicenter Registry Study.JACC. Asia · 2022Article
- Trends in computed tomography aortography and acute aortic syndrome in an emergency department within Aotearoa New Zealand.Emergency medicine Australasia : EMA · 2022Article
- Comparison Between Bicuspid and Tricuspid Aortic Regurgitation: Presentation, Survival, and Aorta Complications.JACC. Asia · 2022Article
- Incidence and Survival of Aortic Dissection in Urban China: Results from the National Insurance Claims for Epidemiological Research (NICER) Study.The Lancet regional health. Western Pacific · 2021Article
- Risk of Aortic Aneurysm and Dissection in Patients with Tuberculosis: A Nationwide Population-Based Cohort Study.International journal of environmental research and public health · 2021Article
- Risk of aortic dissection or aneurysm in patients with gallstone disease: a retrospective cohort study in Taiwan.BMJ open · 2021Article
- Long-Term Outcomes of Acute Kidney Injury After Different Types of Cardiac Surgeries: A Population-Based Study.Journal of the American Heart Association · 2021Article
- Incidence and Mortality Rates of Thoracic Aortic Dissection in Korea - Inferred from the Nationwide Health Insurance Claims.Journal of Korean medical science · 2020Article
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Corrections and comments
- Erratum issued
- Erratum issued
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute aortic dissection (AD) is a catastrophic condition associated with a high rate of mortality. However, current epidemiological information regarding AD remains sparse. The objective of the present study was to investigate the current epidemiological profile and medication utilization patterns associated with aortic dissection in Taiwan.In this population-based study, we identified cases of AD diagnosed during 2005 to 2012 in the complete Taiwan National Health Insurance (NHI) Research Database. Patients with AD were identified using the International Classification of Disease, Ninth Revision (ICD-9) code 441.0, and surgical interventions were defined using NHI procedure codes.A total of 9092 individuals with a mean age of 64.4 ± 15.1 years were identified. The cases were divided into 3 groups: Group A included 2340 patients (25.74%) treated surgically for type A AD; Group B included 1144 patients (12.58%) treated surgically for type B AD, and Group C included 5608 patients (61.68%) with any type of AD treated with medical therapy only. The average annual incidence of AD was 5.6 per 100,000 persons, and the average prevalence was 19.9 per 100,000 persons. Hypertension was the most common risk factor, followed by coronary artery disease and chronic obstructive pulmonary disease. Within 1 year of AD diagnosis, 92% of patients were taking antihypertensive medication. Calcium channel blockers were the most frequently prescribed antihypertensive medication for long-term observation in Taiwan.The annual trends revealed statistically significant increases in the numbers and percentages of prevalence, incidence, and mortality. Changes in patients' drug utilization in patterns were observed after AD diagnosis. Our study provides a local profile that supports further in-depth analyses in AD-affected populations.
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