Evidence map›Paper›PMID 26355266›Full record

ReviewJournal of clinical and translational hepatology2014

Biomarker-based MicroRNA Therapeutic Strategies for Hepatocellular Carcinoma.

Min Yao, Li Wang, Yao Yao, Hong-Bing Gu, Deng-Fu Yao

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of clinical and translational hepatology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. [miRNA expression profiles in serum exosome from patients with hepatitis B virus related hepatocellular carcinoma].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2019
    Article
  3. [Research progress of deubiquitinating enzyme CYLD to regulate liver-related diseases].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2019
    Review
  4. Article
  5. [MicroRNA-30a inhibits proliferation of hepatocellular carcinoma cells via targeted regulation of forkhead-box protein A1].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2017
    Article
  6. Article
  7. Article
  8. [Research advances in epithelial - mesenchymal transition in hepatocellular carcinoma].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2017
    Review
  9. Article
  10. Article
  11. Article
  12. [Role of inhibition of nuclear factor-kappa B gene transcription by specific miRNA in reversing multi-drug resistance of liver cancer].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2016
    Article
  13. Article
  14. The overexpression of miR-30a affects cell proliferation of chondrosarcoma via targeting Runx2.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2016
    Article
  15. Article
  16. The upregulation of miRNA-146a inhibited biological behaviors of ESCC through inhibition of IRS2.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2016
    Article
  17. Article
  18. [Down-regulated clusterin expression enhances sensitivity of hepatoma cells to anti-cancer drugs].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2015
    Article
  19. [Clinical significance of abnormal Wnt signaling pathway expression in hepatitis and hepatocellular carcinoma].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Min YaoResearch Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong, Jiangsu, China ; Department of Immunology, Medical School of Nantong University, Nantong, Jiangsu, China.
Li WangDepartment of Medical Informatics, Medical School of Nantong University, Nantong, Jiangsu, China.
Yao YaoThe Hospital of Nantong Maternal and Child Care Service, Nantong, Jiangsu, China.
Hong-Bing GuThe Hospital of Nantong Maternal and Child Care Service, Nantong, Jiangsu, China.
Deng-Fu YaoResearch Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong, Jiangsu, China.
Nantong University · CNAffiliated Hospital of Nantong University · CNNantong Maternity and Child Health Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, microRNAs (miRNAs) have emerged as key factors involved in a series of biological processes, ranging from embryogenesis to programmed cell death. Its link to aberrant expression profiles has rendered it a potentially attractive tool for the diagnosis, prognosis, or treatment of various diseases. Accumulating evidence has indicated that miRNAs act as tumor suppressors in hepatocyte malignant transformation by regulating development, differentiation, proliferation, and tumorigenesis. Here, we summarize recent progress in the development of novel biomarker-based miRNA therapeutic strategies for hepatocellular carcinoma (HCC).

Indexed as

Hepatocellular carcinomaMicroRNAMolecular targetTherapy

Identifiers

PMID26355266
PMCPMC4521238
OpenAlexW2334541758

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.